Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 5/20 | 0.58 |
| ▸ | CES1 | P23141 | 5/20 | 0.58 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19212992 | 0.91 | CES2 (0.56) | CES2CES1CYP11B1CYP11B2L3MBTL1 | |
| SCHEMBL12963563 | 0.87 | CES2 (0.52) | CES2CES1L3MBTL1LMNAMAPT | |
| SCHEMBL19212944 | 0.85 | HPGD (0.64) | CES2CES1CYP11B1CYP11B2HPGD | |
| SCHEMBL26813754 | 0.80 | CYP11B1 (0.48) | CES2CES1CYP11B1CYP11B2L3MBTL1 | |
| SCHEMBL19212935 | 0.80 | CYP11B1 (0.64) | CES2CES1CYP11B1CYP11B2HPGD | |
| SCHEMBL19212940 | 0.79 | CYP11B1 (0.64) | CYP11B1CYP11B2HPGDELANE | |
| SCHEMBL197094 | 0.78 | KMT2A (0.63) | CES2CES1L3MBTL1LMNAALOX15 | |
| SCHEMBL19212998 | 0.77 | CYP11B1 (0.58) | CES2CES1CYP11B1CYP11B2HPGD | |
| SCHEMBL10765485 | 0.77 | CES2 (0.55) | CES2CES1LMNAMAPTKMT2A | |
| SCHEMBL13274370 | 0.76 | HPGD (0.46) | CYP11B1CYP11B2L3MBTL1LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798311-A | INSECTICIDES | ROHM AND HAAS COMPANY (US) | 1998-08-25 | — | — | US | disclosed |
| EP-0466408-A1 | N-aryl-3-aryl-4-substituted-4,5-dihydro-1H-pyrazole-1-carboxamides and processes for their production | ROHM AND HAAS COMPANY (US) | 1992-01-15 | — | — | EP | disclosed |