SCHEMBL197094

SCHEMBL197094

O=C(Oc1ccccc1)c1ccc(Cl)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.63
ALOX15 P16050 1/20 0.63
PARP10 Q53GL7 1/20 0.59
MEN1 O00255 4/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
PRSS1 P07477 1/20 0.57
ACR P10323 1/20 0.57
TMPRSS15 P98073 1/20 0.57
CES2 O00748 1/20 0.55
CES1 P23141 1/20 0.55
NSD2 O96028 1/20 0.55
MAPT P10636 4/20 0.54
NPC1 O15118 1/20 0.53
NR1I2 O75469 1/20 0.53
LMNA P02545 1/20 0.53
TP53 P04637 1/20 0.53
AHR P35869 1/20 0.53
RAB9A P51151 1/20 0.53
TAAR1 Q96RJ0 1/20 0.53
HTT P42858 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6032517 0.93 PARP10 (0.57) KMT2AALOX15PARP10MEN1SMN1; SMN2
SCHEMBL4425652 0.92 PARP10 (0.65) KMT2AALOX15PARP10MEN1SMN1; SMN2
Iodobenzene SCHEMBL27765364 0.91 KMT2A (0.55) KMT2AALOX15PARP10MEN1SMN1; SMN2
SCHEMBL9683516 0.90 KMT2A (0.69) KMT2AALOX15PARP10MEN1SMN1; SMN2
SCHEMBL10599787 0.90 KMT2A (0.69) KMT2AALOX15PARP10MEN1SMN1; SMN2
SCHEMBL610755 0.90 KMT2A (0.69) KMT2AALOX15PARP10MEN1SMN1; SMN2
SCHEMBL28003430 0.90 KMT2A (0.69) KMT2AALOX15PARP10MEN1SMN1; SMN2
SCHEMBL70034 0.89 PARP10 (0.70) KMT2AALOX15PARP10MEN1SMN1; SMN2
SCHEMBL7739094 0.89 PARP10 (0.57) KMT2AALOX15PARP10MEN1SMN1; SMN2
SCHEMBL8718766 0.86 ALOX15 (0.65) KMT2AALOX15PARP10MEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6472498-B2 COLORLESS UBE INDUSTRIES, LTD. (JP) 2002-10-29 US claimed
EP-0832910-B1 Process for producing a polycarbonate UBE INDUSTRIES (JP) 2002-06-26 EP claimed
US-20020019512-A1 Diaryl carbonate product and production of polycarbonate UBE INDUSTRIES, LTD. 2002-02-14 US claimed
EP-1178033-A1 Process for the purification of diaryl carbonate and process for the production of polycarbonate Ube Industries, Ltd. (JP) 2002-02-06 EP claimed
US-5922827-A Process for producing a polycarbonate UBE INDUSTRIES, LTD. (JP) 1999-07-13 US claimed
EP-0832910-A2 Process for producing a polycarbonate UBE INDUSTRIES, LTD. (JP) 1998-04-01 EP claimed
JP-3127753-A None JP disclosed
CN-114920637-B Preparation process of 4-chloro-4' -hydroxybenzophenone 江苏科技大学 2023-11-21 CN disclosed
CN-112110817-B Method for preparing diaryl ester compound by high-efficiency catalysis of palladium pyridine 陕西师范大学 2022-07-26 CN disclosed
US-11136421-B2 Solid catalyst component for use in olefin polymerisation, catalyst, and application thereof BEIJING LIHE TECHNOLOGY LTD (CN) 2021-10-05 US disclosed
CN-112110817-A Method for preparing diaryl ester compound by high-efficiency catalysis of palladium pyridine 陕西师范大学 2020-12-22 CN disclosed
US-20200071430-A1 SOLID CATALYST COMPONENT FOR USE IN OLEFIN POLYMERISATION, CATALYST, AND APPLICATION THEREOF BEIJING LIHE TECH LTD (CN) 2020-03-05 US disclosed
CN-106458834-B Diphenyl carbonate and method for producing same, catalyst and method for producing, recovering and reusing same, and polycarbonate 三菱化学株式会社 2019-10-25 CN disclosed
EP-0511641-A2 Resin for bonding polyarylene sulfide and adhesive KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1992-11-04 EP disclosed
JP-H03127753-A PRODUCTION OF 4-CHLORO-4'-HYDROXYBENZOPHENONES MITSUBISHI KASEI CORP 1991-05-30 JP disclosed
EP-0057503-B1 PRODUCTION OF HYDROXY ARYLOPHENONES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-03-20 EP disclosed
US-4495311-A METAL CHELATES OR SALTS AND BENZOYL COMPOUNDS AS ADDIVES PRINCETON POLYMER LABORATORIES, INC. (US) 1985-01-22 US disclosed
US-4453010-A Production of hydroxy arylophenones IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-06-05 US disclosed
EP-0057503-A1 Production of hydroxy arylophenones IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-08-11 EP disclosed
US-3981856-A BIODEGRADATION, ADDITION POLYMERS PRINCETON POLYMER LABORATORIES, INCORPORATED (US) 1976-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019512-A1 Diaryl carbonate product and production of polycarbonate PKD1, APC, PKD2 KMT2A 1220/4885ALOX15 3763/4885PARP10 1355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.