Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.58 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.58 |
| ▸ | IL1RN | P18510 | 4/20 | 0.58 |
| ▸ | TACR1 | P25103 | 10/20 | 0.57 |
| ▸ | NMBR | P28336 | 2/20 | 0.57 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669151 | 0.89 | MEN1 (0.58) | NMBR | |
| SCHEMBL6264591 | 0.89 | BCHE (0.56) | TACR1NMBRMAPT | |
| SCHEMBL28260558 | 0.86 | MEN1 (0.66) | ERAP2ERAP1IL1RNTACR1LNPEP | |
| SCHEMBL28260561 | 0.86 | MEN1 (0.66) | ERAP2ERAP1IL1RNTACR1LNPEP | |
| SCHEMBL3848569 | 0.86 | MEN1 (0.63) | MAPT | |
| SCHEMBL3848966 | 0.86 | MEN1 (0.63) | MAPT | |
| SCHEMBL3848969 | 0.86 | MEN1 (0.63) | MAPT | |
| SCHEMBL8227227 | 0.85 | MEN1 (0.64) | ERAP2ERAP1IL1RNTACR1LNPEP | |
| SCHEMBL6245123 | 0.85 | MEN1 (0.62) | MAPT | |
| SCHEMBL6244061 | 0.85 | MEN1 (0.62) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708771-B1 | BENZYLOXYQUINUCLIDINES AS SUBSTANCE P ANTAGONISTS | PFIZER (US) | 1998-10-07 | — | — | EP | disclosed |