Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 3/20 | 0.54 |
| ▸ | MMP3 | P08254 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 2/20 | 0.54 |
| ▸ | MMP8 | P22894 | 2/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | CCKBR | P32239 | 1/20 | 0.52 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.52 |
| ▸ | MMP7 | P09237 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 2/20 | 0.52 |
| ▸ | NMBR | P28336 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5388724 | 0.94 | MMP2 (0.51) | BCHEMAPTTP53LMNATHRB | |
| SCHEMBL5388718 | 0.94 | MMP2 (0.51) | BCHEMAPTTP53LMNATHRB | |
| SCHEMBL5388714 | 0.94 | MMP2 (0.51) | BCHEMAPTTP53LMNATHRB | |
| SCHEMBL8669153 | 0.89 | ERAP2 (0.58) | MAPTTACR1NMBR | |
| SCHEMBL6245123 | 0.88 | MEN1 (0.62) | BCHEMAPTMMP2MMP1MMP8 | |
| SCHEMBL8384759 | 0.88 | MEN1 (0.62) | BCHEMAPTMMP2MMP1MMP8 | |
| SCHEMBL28377319 | 0.88 | MEN1 (0.62) | BCHEMAPTMMP2MMP1MMP8 | |
| SCHEMBL8384762 | 0.88 | MEN1 (0.62) | BCHEMAPTMMP2MMP1MMP8 | |
| SCHEMBL6244059 | 0.88 | MEN1 (0.62) | BCHEMAPTMMP2MMP1MMP8 | |
| SCHEMBL6244061 | 0.88 | MEN1 (0.62) | BCHEMAPTMMP2MMP1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1113795-B1 | TRYPTOPHANYL ESTERS AND THEIR N-ACYL DERIVATIVES FOR THE PREVENTION AND TREATMENT OF DISEASES CAUSED OR EXACERBATED BY OXIDATION PROCESSES | MAX PLANCK GESELLSCHAFT (DE) | 2005-07-13 | — | — | EP | claimed |
| US-20040176436-A1 | Tryptophanyl-esters and their N-acyl derivatives for preventing and treating diseases caused or aggravated by oxidation processes | BEHL CHRISTIAN (DE) | 2004-09-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176436-A1 | Tryptophanyl-esters and their N-acyl derivatives for preventing and treating diseases caused or aggravated by oxidation processes | AADAT, KYNU, AADAC | BCHE 325/4885MAPT 521/4885TP53 815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.