Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.51 |
| ▸ | HINT1 | P49773 | 5/20 | 0.48 |
| ▸ | GSK3A | P49840 | 2/20 | 0.46 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | TYMP | P19971 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 1/20 | 0.43 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10904154 | 0.90 | TAAR1 (0.57) | TAAR1HINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL7100209 | 0.90 | TYMP (0.54) | TAAR1HINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL2115345 | 0.88 | TAS1R3 (0.52) | TAAR1HINT1TYMP | |
| SCHEMBL8916727 | 0.86 | POLB (0.45) | TAAR1HINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL441420 | 0.86 | TAS1R3 (0.44) | TAAR1HINT1TYMP | |
| SCHEMBL2116135 | 0.86 | TYMP (0.38) | TAAR1HINT1TYMPHPGD | |
| SCHEMBL5580212 | 0.83 | ADORA1 (0.55) | — | |
| SCHEMBL8602348 | 0.81 | TYMP (0.48) | TAAR1HINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL2111737 | 0.81 | PRMT5 (0.45) | TYMP | |
| SCHEMBL8431261 | 0.80 | TAAR1 (0.54) | TAAR1HINT1GSK3ARPS6KA3MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405913-B1 | Hydrophobic nucleic acid probe | CHIRON CORP (US) | 1998-12-23 | — | — | EP | disclosed |
| US-5702893-A | BINDING TARGET POLYNUCLEOTIDE IN SAMPLE USING AS ASSAY REAGENT SUBSTRATE HAVING POLYNUCLEOTIDE CAPTURE PROBE BOUND THERETO BY HYDROPHOBIC MOIETY, HYBRIDIZING | CHIRON CORPORATION (US) | 1997-12-30 | — | — | US | disclosed |
| US-5552280-A | Hydrophobic nucleic acid probes | CHIRON CORPORATION (US) | 1996-09-03 | — | — | US | disclosed |
| WO-1991000288-A1 | HYDROPHOBIC NUCLEIC ACID PROBE | CHIRON CORP (US) | 1991-01-10 | — | — | WO | disclosed |
| EP-0405913-A2 | Hydrophobic nucleic acid probe | CHIRON CORPORATION (US) | 1991-01-02 | — | — | EP | disclosed |