Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TYMP | P19971 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.40 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.40 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.40 |
| ▸ | HINT1 | P49773 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7195662 | 0.90 | POLB (0.39) | POLBTYMPTAAR1P2RY2P2RY4 | |
| SCHEMBL8574965 | 0.89 | HPGD (0.46) | POLBTYMPTAAR1P2RY2P2RY4 | |
| SCHEMBL2113123 | 0.87 | KDM4E (0.50) | POLBTYMPTAAR1HINT1TAS1R3 | |
| SCHEMBL8669174 | 0.86 | TAAR1 (0.51) | TYMPTAAR1HINT1HPGDSTING1 | |
| SCHEMBL14556177 | 0.85 | TYMP (0.38) | TYMPSTING1 | |
| SCHEMBL9015823 | 0.84 | ADORA1 (0.44) | POLBTYMPSTING1 | |
| SCHEMBL15954504 | 0.81 | TYMP (0.38) | TYMP | |
| SCHEMBL7199260 | 0.80 | POLB (0.41) | POLBP2RY2P2RY4P2RY6PDE3A | |
| SCHEMBL30712246 | 0.78 | POLB (0.58) | POLBP2RY2P2RY4P2RY6STING1 | |
| SCHEMBL1687292 | 0.78 | TK1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703223-A | Solid phase synthesis of oligonucleotides with stereospecific substituted phosphonate linkages by pentavalent grignard coupling | THOMAS JEFFERSON UNIVERSITY (US) | 1997-12-30 | — | — | US | disclosed |