SCHEMBL8669335

SCHEMBL8669335

CC(C)(C)[Si](C)(C)OC[C@@H](O)[C@H](CC(=O)O)O[Si](C)(C)C(C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PGD P52209 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29402604 0.81 PGD (0.31) PGD
SCHEMBL3710988 0.79 PGD (0.33) PGD
SCHEMBL3710989 0.79 PGD (0.33) PGD
SCHEMBL22289099 0.79 PGD (0.33) PGD
SCHEMBL6301406 0.78 SLC22A6 (0.43) PGD
SCHEMBL2847564 0.78 PGD (0.32) PGD
SCHEMBL6301409 0.78 SLC22A6 (0.43) PGD
SCHEMBL14993927 0.76 TDP1 (0.30) PGD
SCHEMBL14993926 0.76 TDP1 (0.30) PGD
SCHEMBL30287805 0.75 MAPK1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5750735-A CHEMICAL INTERMEDIATES FOR ANTIBIOTICS AMERICAN CYANAMID COMPANY (US) 1998-05-12 US disclosed
US-5623081-A USING BENZYLOXYACETALDEHYDE DIMETHYL ETHER, HALOGENATED 1-PHENYLMETHOXY-4-PENTEN-2-OL; CYCLIZATION LIN YANG-I (US) 1997-04-22 US disclosed
US-5602118-A A 2-((2-SUBSTITUTED ALKYL)FUR-3-YL)-THIO-),3-CARBOXY-2-CARBOPENEM DERIVATIVES; EFFECTIVE AGAINST BETA-LACTAM ANTIBIOTIC-RESISTANT BACTERIA AMERICAN CYANAMID COMPANY (US) 1997-02-11 US disclosed
EP-0617036-A2 Novel 2-thiosubstituted carbapenems AMERICAN CYANAMID COMPANY (US) 1994-09-28 EP disclosed