SCHEMBL6301406

SCHEMBL6301406

CC(C)(C)[Si](C)(C)OC[C@H](O)CC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.43
PGD P52209 2/20 0.39
MAPT P10636 1/20 0.38
GABRR1 P24046 2/20 0.38
LMNA P02545 1/20 0.38
GPR84 Q9NQS5 4/20 0.35
SMN1; SMN2 Q16637 1/20 0.31
ADRB2 P07550 1/20 0.30
ADRB1 P08588 1/20 0.30
ADRB3 P13945 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6301409 1.00 SLC22A6 (0.43) SLC22A6PGDMAPTGABRR1LMNA
SCHEMBL4420207 0.82 MAPK1 (0.32)
SCHEMBL633699 0.81 PGD (0.39) PGD
SCHEMBL16689224 0.80 PGD (0.34) PGD
SCHEMBL15142159 0.80 FFAR4 (0.41) GPR84
SCHEMBL22289099 0.79 PGD (0.33) PGDLMNASMN1; SMN2
SCHEMBL3710989 0.79 PGD (0.33) PGDLMNASMN1; SMN2
SCHEMBL3710988 0.79 PGD (0.33) PGDLMNASMN1; SMN2
SCHEMBL8669335 0.78 PGD (0.34) PGD
SCHEMBL17709437 0.77 CYP2D6 (0.38) ADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6897324-B2 Process for the preparation of 11-oxaprostaglandins and intermediates therein CHIROTECH TECHNOLOGY LIMITED (GB) 2005-05-24 US disclosed
US-20030166948-A1 Process for the preparation of 11-oxaprostaglandins and intermediates therein CHIROTECH TECHNOLOGY LIMITED (GB) 2003-09-04 US disclosed
EP-1282627-A1 PROCESS FOR THE PREPARATION OF 11-OXAPROSTAGLANDINS AND INTERMEDIATES THEREIN Chirotech Technology Limited (GB) 2003-02-12 EP disclosed
WO-2001087897-A1 PROCESS FOR THE PREPARATION OF 11-OXAPROSTAGLANDINS AND INTERMEDIATES THEREIN CHIROTECH TECHNOLOGY LIMITED (GB) 2001-11-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030166948-A1 Process for the preparation of 11-oxaprostaglandins and intermediates therein CYP4A11, PTGER1, PTGIS SLC22A6 3885/4885PGD 301/4885MAPT 4883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.