Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27678799 | 0.91 | LMNA (0.54) | LMNATDP1MAPK1HIF1ATSHR | |
| SCHEMBL8351678 | 0.87 | LMNA (0.61) | LMNATDP1MAPK1HIF1ATSHR | |
| SCHEMBL21104459 | 0.87 | LMNA (0.61) | LMNATDP1MAPK1HIF1ATSHR | |
| SCHEMBL1164342 | 0.85 | LMNA (0.59) | LMNATDP1MAPK1HIF1ATSHR | |
| SCHEMBL16213997 | 0.84 | LMNA (0.57) | LMNATDP1MAPK1HIF1ATSHR | |
| SCHEMBL6934530 | 0.83 | LMNA (0.65) | LMNATDP1MAPK1HIF1ATSHR | |
| SCHEMBL1995169 | 0.83 | TDP1 (0.63) | LMNATDP1MAPK1HIF1ATSHR | |
| SCHEMBL11192789 | 0.83 | LMNA (0.56) | LMNATDP1MAPK1HIF1ATSHR | |
| SCHEMBL20282186 | 0.82 | LMNA (0.64) | LMNATDP1MAPK1HIF1ATSHR | |
| SCHEMBL25339994 | 0.81 | LMNA (0.62) | LMNATDP1MAPK1HIF1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750778-A | FLUOROALKANOIC ACIDS AND DERIVATIVES | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |
| EP-0468681-B1 | Alfa-fluorocarboxylic acid derivatives as intermediates for the preparation of fungicides | ZENECA LTD (GB) | 1995-05-24 | — | — | EP | disclosed |
| EP-0468681-A1 | Alfa-fluorocarboxylic acid derivatives as intermediates for the preparation of fungicides | ZENECA LIMITED (GB) | 1992-01-29 | — | — | EP | disclosed |