SCHEMBL6934530

SCHEMBL6934530

CC(C)(C)CCOC(=O)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.65
TDP1 Q9NUW8 4/20 0.63
MAPK1 P28482 1/20 0.56
HIF1A Q16665 1/20 0.56
SLC6A3 Q01959 2/20 0.52
KMT2A Q03164 2/20 0.52
SLC6A2 P23975 1/20 0.52
TSHR P16473 3/20 0.51
ALDH1A1 P00352 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
HTR1A P08908 1/20 0.50
CYP2D6 P10635 1/20 0.50
SCN1A P35498 1/20 0.50
SCN5A Q14524 1/20 0.50
SCN2A Q99250 1/20 0.50
SCN3A Q9NY46 1/20 0.50
ADRB2 P07550 1/20 0.50
ADRB1 P08588 1/20 0.50
ADRB3 P13945 1/20 0.50
HSD17B10 Q99714 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22198592 0.90 TSHR (0.53) LMNATDP1MAPK1SLC6A2TSHR
SCHEMBL11887308 0.90 KDM4E (0.55) LMNATDP1MAPK1HIF1AALDH1A1
SCHEMBL21113688 0.89 TDP1 (0.70) LMNATDP1MAPK1HIF1ASLC6A3
SCHEMBL12630627 0.88 TDP1 (0.73) LMNATDP1MAPK1HIF1ASLC6A3
SCHEMBL25339994 0.87 LMNA (0.62) LMNATDP1MAPK1HIF1ASLC6A3
SCHEMBL3400673 0.87 LMNA (0.62) LMNATDP1MAPK1HIF1ASLC6A3
SCHEMBL18522327 0.87 MAPT (0.50) LMNATDP1MAPK1HIF1ASLC6A2
SCHEMBL26622236 0.86 TDP1 (0.71) LMNATDP1MAPK1HIF1ASLC6A3
SCHEMBL17615513 0.86 TDP1 (0.71) LMNATDP1MAPK1HIF1ASLC6A3
SCHEMBL21104459 0.86 LMNA (0.61) LMNATDP1MAPK1HIF1ASLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3517555-B1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2024-11-27 EP claimed
EP-3517553-B1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2023-11-08 EP claimed
US-11325994-B2 Catalyst component for olefin polymerization, catalyst, and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2022-05-10 US claimed
CN-107868147-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-09-15 CN claimed
CN-107868149-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-07-24 CN claimed
US-10662268-B2 Catalyst component for olefin polymerization, catalyst, and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2020-05-26 US claimed
US-20190256623-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST, AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-08-22 US claimed
EP-3517555-A1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF China Petroleum&Chemical Corporation (CN) 2019-07-31 EP claimed
EP-3517553-A1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF China Petroleum&Chemical Corporation (CN) 2019-07-31 EP claimed
US-20190211119-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST, AND USE THEREOF BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-07-11 US claimed
EP-3517555-B1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2024-11-27 EP disclosed
EP-3517553-B1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2023-11-08 EP disclosed
US-11325994-B2 Catalyst component for olefin polymerization, catalyst, and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2022-05-10 US disclosed
US-20210171688-A1 BIOCOMPATIBLE COPOLYMER, CURABLE COMPOSITION, BIOCOMPATIBLE COATING LAYER AND BIOCOMPATIBLE DEVICE INCLUDING THE SAME NATIONAL CENTRAL UNIVERSITY (TW) 2021-06-10 US disclosed
US-10815228-B2 Aztreonam derivatives and uses thereof ARIXA PHARMACEUTICALS, INC. (US) 2020-10-27 US disclosed
US-20070185155-A1 Muscarinic acetylcholine receptor antagonists GLAXO GROUP LIMITED (GB) 2007-08-09 US disclosed
US-20070179100-A1 Protected monomers ALNYLAM PHARMACEUTICALS, INC. 2007-08-02 US disclosed
US-6505942-B2 Anti-reflection material, polarization film, and production methods therefor TOMOEGAWA PAPER CO., LTD. (JP) 2003-01-14 US disclosed
US-20020034008-A1 Anti-reflection material, polarization film, and production methods therefor TOMOEGAWA PAPER CO., LTD. (JP) 2002-03-21 US disclosed
US-6191884-B1 COATING CONDUCTIVE MATERIALS INCLUDING INDIUM TIN OXIDE POWDER AND RESIN TOMOEGAWA PAPER CO., LTD. (JP) 2001-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10815228-B2 Aztreonam derivatives and uses thereof MGAM, ABCG2, SI LMNA 2449/4885TDP1 2196/4885MAPK1 4720/4885
US-20070179100-A1 Protected monomers PCNA, POLN, PARP1 LMNA 111/4885TDP1 263/4885MAPK1 4090/4885
US-20070185155-A1 Muscarinic acetylcholine receptor antagonists CHRM3, CHRNG, CHRM2 LMNA 4137/4885TDP1 3416/4885MAPK1 4667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.