Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 6/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CENPE | Q02224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8667760 | 0.99 | MAPT (0.34) | MAPTTHRBKMT2ABDKRB2POLB | |
| Hydrochloric Acid SCHEMBL8670170 | 0.90 | MAPT (0.34) | MAPTTHRBKMT2ABDKRB2GPR139 | |
| SCHEMBL8669110 | 0.82 | BDKRB2 (0.35) | BDKRB2 | |
| SCHEMBL8475069 | 0.79 | SMN1; SMN2 (0.37) | MAPTTHRBKMT2APOLBGPR139 | |
| Hydrochloric Acid SCHEMBL8477672 | 0.78 | SMN1; SMN2 (0.36) | MAPTTHRBKMT2APOLBGPR139 | |
| SCHEMBL8671788 | 0.76 | BDKRB2 (0.33) | BDKRB2 | |
| SCHEMBL8667208 | 0.70 | CENPE (0.35) | BDKRB2CENPE | |
| Hydrochloric Acid SCHEMBL8669829 | 0.69 | CENPE (0.34) | BDKRB2CENPE | |
| SCHEMBL8669822 | 0.69 | BDKRB2 (0.34) | BDKRB2 | |
| SCHEMBL8559050 | 0.69 | NPC1 (0.36) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750699-A | HALOGENATING OF CORRESPONDING COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |