Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | SCN4A | P35499 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1811045 | 0.80 | LMNA (0.53) | LMNACYP2D6L3MBTL1ADRB2ADRB1 | |
| SCHEMBL9564637 | 0.76 | LMNA (0.68) | LMNASCN4AMAOAPTGS1CYP2D6 | |
| SCHEMBL7268804 | 0.75 | LMNA (0.58) | LMNASCN4AMAOAPTGS1CYP2D6 | |
| SCHEMBL3909668 | 0.75 | LMNA (0.49) | LMNASCN4AMAOAPTGS1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7428095 | 0.74 | LMNA (0.56) | LMNASCN4AMAOAPTGS1CYP2D6 | |
| SCHEMBL851069 | 0.74 | LMNA (0.66) | LMNASCN4AMAOAPTGS1CYP2D6 | |
| SCHEMBL851067 | 0.74 | LMNA (0.66) | LMNASCN4AMAOAPTGS1CYP2D6 | |
| SCHEMBL835106 | 0.74 | LMNA (0.66) | LMNASCN4AMAOAPTGS1CYP2D6 | |
| SCHEMBL5962145 | 0.73 | LMNA (0.46) | LMNASCN4AMAOAPTGS1CYP2D6 | |
| Sulfuric Acid SCHEMBL11626916 | 0.73 | LMNA (0.46) | LMNACYP2D6L3MBTL1ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767778-B1 | 1-PHENOXY-3-N-ALKYLAMINOPROPAN-2-OL HALOGEN DERIVATIVES USEFUL AS MYOCARDIAL beta ADRENERGIC RECEPTOR MARKERS AND AS beta-BLOCKING AGENTS | CIS BIO INT (FR) | 1998-12-16 | — | — | EP | claimed |