Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | MC3R | P41968 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7520020 | 1.00 | CNR2 (0.37) | CNR2ALDH1A1TDP1KCNK3THRB | |
| SCHEMBL11792606 | 0.84 | ALDH1A1 (0.45) | CNR2ALDH1A1TDP1PGRADORA3 | |
| SCHEMBL11787749 | 0.84 | ALDH1A1 (0.45) | CNR2ALDH1A1TDP1PGRADORA3 | |
| SCHEMBL7517738 | 0.83 | TBXA2R (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7517233 | 0.83 | SOAT1 (0.37) | ALDH1A1CNR1KDM4EMEN1KMT2A | |
| SCHEMBL8670432 | 0.83 | SOAT1 (0.37) | ALDH1A1CNR1KDM4EMEN1KMT2A | |
| SCHEMBL7511928 | 0.82 | — | — | |
| SCHEMBL8671901 | 0.82 | — | — | |
| SCHEMBL8938445 | 0.82 | — | — | |
| SCHEMBL9179064 | 0.81 | CNR1 (0.35) | CNR2ALDH1A1CNR1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773654-A | 7-(5-substituted cyclopentyl) and (5-substituted cyclopentenyl) heptyl alcohols, heptylamines and heptanoic acid amides, and method of lowering intraocular pressure in the eye of a mammal by administration of these compounds | ALLERGAN (US) | 1998-06-30 | — | — | US | disclosed |
| US-5674910-A | 7-(5-substituted cyclopentyl) and (5-substituted cyclopentenyl) heptyl alcohols, heptylamines and heptanoic acid amides, and method of lowering intraocular pressure in the eye of a mammal by administration of these novel compounds | ALLERGAN (US) | 1997-10-07 | — | — | US | disclosed |