Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 6/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 5/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697794 | 1.00 | KLK7 (0.39) | KLK7GRM2CTSBCTSSCTSK | |
| SCHEMBL7703728 | 0.90 | NR1H2 (0.38) | KLK7GRM2CTSBCTSSCTSK | |
| SCHEMBL30387509 | 0.88 | FKBP1A (0.39) | KLK7 | |
| SCHEMBL5065670 | 0.88 | KLK7 (0.49) | KLK7MEN1KMT2AKLK5NR1H2 | |
| SCHEMBL8669568 | 0.88 | KLK7 (0.49) | KLK7MEN1KMT2AKLK5NR1H2 | |
| SCHEMBL31486428 | 0.88 | KLK7 (0.49) | KLK7MEN1KMT2AKLK5NR1H2 | |
| SCHEMBL7699900 | 0.86 | KLK7 (0.43) | KLK7KMT2AKLK5NR1H2NR1H3 | |
| SCHEMBL5204187 | 0.85 | OPRK1 (0.44) | KLK7KLK5 | |
| SCHEMBL8667026 | 0.80 | KLK7 (0.48) | KLK7MEN1KMT2AKLK5NR1H2 | |
| SCHEMBL7701458 | 0.80 | MMP13 (0.38) | KLK7MEN1KMT2AKLK5PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002014261-A2 | 4-SUBSTITUTED D-GLUTAMIC ACID DERIVATIVES FOR USE AS ANTIBIOTIC | ELI LILLY AND COMPANY (US) | 2002-02-21 | — | — | WO | disclosed |