Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666422 | 0.91 | POLB (0.56) | EPHX1NPC1RAB9AL3MBTL1HTT | |
| SCHEMBL1665108 | 0.87 | NPC1 (0.47) | EPHX1NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL3766611 | 0.83 | KMT2A (0.50) | MAPTHTTALDH1A1KMT2AMEN1 | |
| SCHEMBL3648241 | 0.82 | LMNA (0.50) | EPHX1NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL9725165 | 0.80 | SMN1; SMN2 (0.44) | EPHX1NPC1RAB9AMAPTHTT | |
| SCHEMBL5481186 | 0.80 | RAB9A (0.34) | EPHX1NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL5472831 | 0.80 | RAB9A (0.33) | EPHX1NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL8668377 | 0.79 | LMNA (0.54) | NPC1RAB9AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL3996276 | 0.78 | SMN1; SMN2 (0.53) | EPHX1NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL5122024 | 0.77 | MAPK1 (0.51) | NPC1RAB9AMAPTHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750552-A | ANTIULCER AGENTS | ARAX CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0736527-A1 | Imadazoline derivative, possible tautomer thereof, process of manufacturing therefor, and vulnerary including such derivative or tautomer | ARAX CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |