Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 4/20 | 0.44 |
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
| ▸ | CTSL | P07711 | 3/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668743 | 0.85 | SYK (0.45) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL8666812 | 0.80 | LMNA (0.46) | CTSKCTSSCTSLCTSBLMNA | |
| SCHEMBL5218083 | 0.80 | SYK (0.57) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL12067897 | 0.78 | LMNA (0.56) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL6647168 | 0.78 | LMNA (0.56) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL5019087 | 0.77 | LMNA (0.61) | SYKCTSSCTSLLMNASMN1; SMN2 | |
| SCHEMBL27268626 | 0.76 | LMNA (0.54) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL19390721 | 0.75 | SMN1; SMN2 (0.52) | SYKCTSKCTSSCTSLLMNA | |
| SCHEMBL7378563 | 0.74 | SYK (0.57) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL6216286 | 0.74 | LMNA (0.58) | SYKCTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5853699-A | Use of tetra azacycle complexes as x-ray diagnostic agents for the liver and gallbladder | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-12-29 | — | — | US | disclosed |