Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669587 | 0.85 | SYK (0.45) | SYKL3MBTL1MAPTSMN1; SMN2LMNA | |
| SCHEMBL6647168 | 0.81 | LMNA (0.56) | SYKSMN1; SMN2LMNAKMT2AHTT | |
| SCHEMBL12067897 | 0.81 | LMNA (0.56) | SYKSMN1; SMN2LMNAKMT2AHTT | |
| SCHEMBL8770412 | 0.81 | SMN1; SMN2 (0.46) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL5218083 | 0.80 | SYK (0.57) | SYKL3MBTL1MAPTSMN1; SMN2LMNA | |
| SCHEMBL5019087 | 0.79 | LMNA (0.61) | SYKL3MBTL1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL8668099 | 0.79 | MEN1 (0.54) | MAPTSMN1; SMN2LMNAMMEACE | |
| SCHEMBL8668738 | 0.79 | CTRB1 (0.52) | SYKSMN1; SMN2MMEACECPA1 | |
| SCHEMBL19390721 | 0.77 | SMN1; SMN2 (0.52) | SYKL3MBTL1MAPTSMN1; SMN2LMNA | |
| SCHEMBL8669072 | 0.77 | LMNA (0.56) | L3MBTL1MAPTSMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5853699-A | Use of tetra azacycle complexes as x-ray diagnostic agents for the liver and gallbladder | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-12-29 | — | — | US | disclosed |