Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.72 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.72 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8646512 | 0.84 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2FFAR1AKR1B1 | |
| SCHEMBL8650159 | 0.81 | CYSLTR1 (0.74) | CYSLTR1CYSLTR2FFAR1AKR1B1ALOX5 | |
| SCHEMBL7594815 | 0.79 | CYSLTR2 (0.49) | CYSLTR1CYSLTR2FFAR1AKR1B1ALOX5 | |
| SCHEMBL7599131 | 0.78 | CYSLTR2 (0.49) | CYSLTR1CYSLTR2FFAR1AKR1B1ALOX5 | |
| SCHEMBL7599144 | 0.78 | CYSLTR2 (0.49) | CYSLTR1CYSLTR2FFAR1AKR1B1ALOX5 | |
| SCHEMBL9460404 | 0.77 | ALOX5 (0.72) | CYSLTR1CYSLTR2FFAR1AKR1B1ALOX5 | |
| SCHEMBL2566640 | 0.77 | CYSLTR2 (0.56) | CYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL7604022 | 0.77 | ALOX5 (0.57) | CYSLTR1CYSLTR2FFAR1AKR1B1ALOX5 | |
| SCHEMBL2564677 | 0.75 | PDE10A (0.54) | CYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL14021559 | 0.75 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2FFAR1AKR1B1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0862557-A1 | SYMMETRICAL bis-HETEROARYLMETHOXYPHENYLALKYL CARBOXYLATES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | Abbott Laboratories (US) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997012867-A1 | SYMMETRICAL bis-HETEROARYLMETHOXYPHENYLALKYL CARBOXYLATES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1997-04-10 | — | — | WO | disclosed |