Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1537950 | 0.93 | ALDH1A1 (0.71) | ALDH1A1LMNATDP1CYP3A4TSHR | |
| SCHEMBL28367269 | 0.93 | ALDH1A1 (0.77) | ALDH1A1LMNATDP1CYP3A4TSHR | |
| SCHEMBL4609262 | 0.93 | LMNA (0.76) | ALDH1A1LMNACYP3A4TSHRCYP2D6 | |
| SCHEMBL10347575 | 0.91 | ALDH1A1 (0.61) | ALDH1A1LMNATDP1CYP3A4TSHR | |
| SCHEMBL7204911 | 0.91 | LMNA (0.81) | ALDH1A1LMNACYP3A4TSHRCYP2D6 | |
| SCHEMBL7209429 | 0.91 | LMNA (0.81) | ALDH1A1LMNACYP3A4TSHRCYP2D6 | |
| SCHEMBL4609318 | 0.91 | LMNA (0.81) | ALDH1A1LMNACYP3A4TSHRCYP2D6 | |
| SCHEMBL11361920 | 0.90 | LMNA (0.65) | ALDH1A1LMNATDP1CYP3A4TSHR | |
| SCHEMBL8854846 | 0.88 | LMNA (0.77) | ALDH1A1LMNACYP3A4TSHRCYP2D6 | |
| SCHEMBL1994316 | 0.88 | LMNA (0.77) | ALDH1A1LMNACYP3A4TSHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808133-A | OXIDATIVE CLEAVAGE OF THE CORRESPONDING MONOOLEFIN | ARAKAWA CHEMICAL INDUSTRIES LTD. (JP) | 1998-09-15 | — | — | US | disclosed |
| US-5670696-A | INTERMEDIATES FOR HIGH MOLECULAR WEIGHT POLYESTERS AND POLYCARBONATES WITH DESIRED PROPERTIES | ARAKAWA CHEMICAL INDUSTIRES LTD. (JP) | 1997-09-23 | — | — | US | disclosed |