Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666205 | 0.85 | OPRM1 (0.39) | SLC6A2ALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL28298245 | 0.83 | OPRM1 (0.48) | SLC6A2SLC6A4SLC6A3OPRM1OPRK1 | |
| SCHEMBL8647058 | 0.77 | ALDH1A1 (0.39) | SLC6A2HSD17B10ALDH1A1ALOX15TSHR | |
| SCHEMBL8664027 | 0.75 | OPRL1 (0.47) | SLC6A2SLC6A4SLC6A3OPRM1OPRK1 | |
| SCHEMBL8664023 | 0.75 | GAA (0.37) | OPRM1OPRK1OPRL1 | |
| SCHEMBL5695341 | 0.74 | OPRL1 (0.60) | OPRM1OPRK1OPRL1 | |
| SCHEMBL17666366 | 0.73 | ALDH1A1 (0.46) | SLC6A2HSD17B10ALDH1A1ALOX15TSHR | |
| SCHEMBL12322575 | 0.70 | ALDH1A1 (0.56) | SLC6A2HSD17B10ALDH1A1ALOX15TSHR | |
| SCHEMBL17409606 | 0.70 | ALDH1A1 (0.56) | SLC6A2HSD17B10ALDH1A1ALOX15TSHR | |
| SCHEMBL21103545 | 0.70 | ALDH1A1 (0.56) | SLC6A2HSD17B10ALDH1A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707747-A | CHARGE TRANSPORT COMPOUNDS | HODOGAYA CHEMICAL CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |