Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 12/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.36 |
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | UGCG | Q16739 | 2/20 | 0.35 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5372599 | 0.90 | LMNA (0.32) | LMNA | |
| SCHEMBL13199409 | 0.90 | LMNA (0.32) | LMNA | |
| SCHEMBL28906948 | 0.80 | TSHR (0.35) | — | |
| SCHEMBL17167771 | 0.79 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL17766095 | 0.79 | CYP1A2 (0.50) | CYP1A2 | |
| SCHEMBL1119487 | 0.78 | CYP1A2 (0.43) | CYP1A2 | |
| SCHEMBL17766144 | 0.77 | CYP1A2 (0.48) | CYP1A2 | |
| SCHEMBL28415916 | 0.76 | CYP1A2 (0.46) | CYP1A2LMNA | |
| SCHEMBL9096554 | 0.76 | CYP1A2 (0.39) | CYP1A2LMNA | |
| SCHEMBL17766114 | 0.76 | SIGMAR1 (0.48) | CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719251-A | Reactive organosilicon compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-02-17 | — | — | US | disclosed |