SCHEMBL8669874

SCHEMBL8669874

CC(C)CCO[Si](CC(C)C)(CC(C)C)OCCC(C)C

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2953531 0.79 HSD17B10 (0.32)
SCHEMBL8666630 0.79 ALDH1A1 (0.37) ALDH1A1CA12CA1CA2CA9
SCHEMBL19356763 0.77 PIK3CD (0.33)
SCHEMBL2953534 0.75 CYP3A4 (0.36) ALDH1A1
SCHEMBL5390926 0.75 ALDH1A1 (0.42) ALDH1A1CA12CA1CA2CA9
SCHEMBL19358548 0.73 ALDH1A1 (0.33) ALDH1A1
SCHEMBL196449 0.72 LMNA (0.32)
SCHEMBL8832566 0.72 ALDH1A1 (0.40) ALDH1A1CA12CA1CA2CA9
SCHEMBL8667093 0.72 ALDH1A1 (0.40) ALDH1A1CA12CA1CA2CA9
SCHEMBL8668475 0.72 ALDH1A1 (0.40) ALDH1A1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2584005-B1 TYPICAL METAL CONTAINING POLYSILOXANE COMPOSITION, PROCESS FOR PRODUCTION OF SAME, AND USES THEREOF TOSOH CORP (JP) 2018-02-21 EP disclosed
EP-2584005-A1 TYPICAL METAL CONTAINING POLYSILOXANE COMPOSITION, PROCESS FOR PRODUCTION OF SAME, AND USES THEREOF Tosoh Corporation (JP) 2013-04-24 EP disclosed
EP-0530814-B1 Method for producing a stereospecific polyolefin TOSOH CORP (JP) 1998-12-16 EP disclosed
EP-0474157-B1 Method for producing a stereospecific polyolefin TOSOH CORP (JP) 1996-12-04 EP disclosed
EP-0475134-B1 Method for producing a stereospecific polyolefin TOSOH CORP (JP) 1996-11-06 EP disclosed
EP-0504744-B1 Method for producing a stereospecific polyolefin TOSOH CORP (JP) 1996-07-17 EP disclosed
US-5489634-A EFFICIENT SELECTIVE CATALYTIC POLYMERIZATION OF ALPHA-OLEFINS YIELDS HIGH MOLECULAR WEIGHT SPHERICAL PARTICLES HAVING HIGH BULK DENSITY, CONTROLLED PARTICLE SIZE AND MOLECULAR WEIGHT DISTRIBUTION TOSOH CORPORATION (JP) 1996-02-06 US disclosed
US-5481056-A Process for the preparation of polyolefins TOSOH CORPORATION (JP) 1996-01-02 US disclosed
US-5468810-A Process for producing a propylene block copolymer UBE INDUSTRIES, LTD. (JP) 1995-11-21 US disclosed
EP-0376145-B1 Method for producing a stereoregular polyolefin TOSOH CORP (JP) 1994-03-23 EP disclosed
EP-0376145-A2 Method for producing a stereoregular polyolefin Tosoh Corporation (JP) 1990-07-04 EP disclosed
US-4829038-A ORGANOSILANE COMPOUND AMOCO CORPORATION (US) 1989-05-09 US disclosed
EP-0275317-A1 PROCESS FOR PRODUCING STEREOREGULAR POLYOLEFINS TOSOH CORPORATION (JP) 1988-07-27 EP disclosed
EP-0095855-B1 PROCESS FOR POLYMERIZING ETHYLENE UBE INDUSTRIES, LTD. (JP) 1987-04-08 EP disclosed
US-4435550-A GRIGNARD REAGENT, ALUMINUM HALIDE, ORGANOSILANE, TITANIUM HALIDE, ESTER, TRIALKYLALUMINUM UBE INDUSTRIES, LTD. (JP) 1984-03-06 US disclosed
US-4420594-A USING AS CATALYST A REACTION PRODUCT OF AN ALUMINUM HALIDE WITH AN ORGANIC SILICON COMPOUND FOLLOWED BY REACTION WITH A GRIGNARD COMPOUND AND TITANIUM TETRAHALIDE UBE INDUSTRIES, LTD. (JP) 1983-12-13 US disclosed
EP-0095855-A1 Process for polymerizing ethylene UBE INDUSTRIES, LTD. (JP) 1983-12-07 EP disclosed
EP-0074276-A1 Process for polymerization of ethylene UBE INDUSTRIES, LTD. (JP) 1983-03-16 EP disclosed
EP-0074275-A1 Process for polymerization of alpha-olefins UBE INDUSTRIES, LTD. (JP) 1983-03-16 EP disclosed
US-4365048-A COORDINATION CATALYST, ALUMINUM COCATALYST, ESTER UBE INDUSTRIES, LTD. (JP) 1982-12-21 US disclosed