SCHEMBL8669907

SCHEMBL8669907

ClP(Cl)OCCc1cccc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.46
CYP2C19 P33261 2/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2D6 P10635 1/20 0.43
MTNR1A P48039 2/20 0.42
NQO2 P16083 1/20 0.42
GPR84 Q9NQS5 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ACP3 P15309 1/20 0.41
CDYL Q9Y232 1/20 0.40
KCNA5 P22460 1/20 0.40
SCN5A Q14524 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL586305 0.80 CYP1A2 (0.52) CYP1A2CYP2C19CYP2C9CYP2D6MTNR1A
SCHEMBL9847159 0.80 CYP1A2 (0.41) CYP1A2CYP2C19CYP2D6NQO2TDP1
SCHEMBL5830948 0.78 GPR84 (0.59) CYP1A2CYP2C19CYP2C9CYP2D6MTNR1A
SCHEMBL9800436 0.78 CYP1A2 (0.58) CYP1A2CYP2C19CYP2C9CYP2D6MTNR1A
SCHEMBL3047898 0.77 CYP1A2 (0.62) CYP1A2CYP2C19CYP2C9CYP2D6MTNR1A
SCHEMBL791971 0.77 CYP1A2 (0.50) CYP1A2CYP2C19CYP2C9CYP2D6MTNR1A
SCHEMBL30487942 0.77 CYP1A2 (0.50) CYP1A2CYP2C19CYP2C9CYP2D6MTNR1A
SCHEMBL16471027 0.77 CYP1A2 (0.48) CYP1A2CYP2C19CYP2C9CYP2D6MTNR1A
SCHEMBL3779748 0.77 CYP1A2 (0.48) CYP1A2CYP2C19CYP2C9CYP2D6MTNR1A
SCHEMBL17435555 0.77 CYP1A2 (0.48) CYP1A2CYP2C19CYP2C9CYP2D6MTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0405913-B1 Hydrophobic nucleic acid probe CHIRON CORP (US) 1998-12-23 EP disclosed
US-5702893-A BINDING TARGET POLYNUCLEOTIDE IN SAMPLE USING AS ASSAY REAGENT SUBSTRATE HAVING POLYNUCLEOTIDE CAPTURE PROBE BOUND THERETO BY HYDROPHOBIC MOIETY, HYBRIDIZING CHIRON CORPORATION (US) 1997-12-30 US disclosed
US-5552280-A Hydrophobic nucleic acid probes CHIRON CORPORATION (US) 1996-09-03 US disclosed
WO-1991000288-A1 HYDROPHOBIC NUCLEIC ACID PROBE CHIRON CORP (US) 1991-01-10 WO disclosed
EP-0405913-A2 Hydrophobic nucleic acid probe CHIRON CORPORATION (US) 1991-01-02 EP disclosed