⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425722 | 0.97 | — | — | |
| SCHEMBL1233523 | 0.86 | NAAA (0.74) | — | |
| SCHEMBL7133119 | 0.86 | NAAA (0.74) | — | |
| SCHEMBL27170957 | 0.86 | NAAA (0.74) | — | |
| SCHEMBL1999782 | 0.86 | NAAA (0.74) | — | |
| SCHEMBL6697263 | 0.86 | NAAA (0.74) | — | |
| SCHEMBL330913 | 0.86 | NAAA (0.74) | — | |
| SCHEMBL2149597 | 0.86 | NAAA (0.74) | — | |
| SCHEMBL484045 | 0.83 | MIF (0.68) | — | |
| SCHEMBL2543807 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536324-B1 | METHOD FOR FORMING AN AMINO ACID THIOHYDANTOIN USING AN N-SUBSTITUTED KETENIMINE ACTIVATOR | PERKIN ELMER CORP (US) | 1998-11-25 | — | — | EP | disclosed |
| EP-0536324-A1 | METHOD FOR FORMING AN AMINO ACID THIOHYDANTOIN USING AN N-SUBSTITUTED KETENIMINE ACTIVATOR | THE PERKIN-ELMER CORPORATION (US) | 1993-04-14 | — | — | EP | disclosed |
| WO-1992000284-A2 | METHOD FOR FORMING AN AMINO ACID THIOHYDANTOIN USING AN N-SUBSTITUTED KETENIMINE ACTIVATOR | APPLIED BIOSYSTEMS, INC. (US) | 1992-01-09 | — | — | WO | disclosed |