Chloromethane

Chloromethane

SCHEMBL8670371

C#CCCC1=C(C(C)(C)c2cccc3c2Cc2ccccc2-3)C=CC1.CCl.[Zr]

nearest known ligand 0.35

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Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.35
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloromethane SCHEMBL8665823 0.77 PNMT (0.33) PNMTNPC1RAB9A
SCHEMBL6917128 0.73 PNMT (0.39) PNMTNPC1RAB9A
SCHEMBL5837265 0.71 PNMT (0.49) PNMTNPC1RAB9A
Bromide SCHEMBL8665180 0.70 PNMT (0.38) PNMTNPC1RAB9A
SCHEMBL8663241 0.69 PNMT (0.40) PNMTNPC1RAB9A
Hydrochloric Acid SCHEMBL8669031 0.69 PNMT (0.34) PNMT
Hydrochloric Acid SCHEMBL8669023 0.69 PNMT (0.34) PNMT
Hydrochloric Acid SCHEMBL8670531 0.68
Bromide SCHEMBL8665184 0.68 PNMT (0.38) PNMTNPC1RAB9A
Hydrochloric Acid SCHEMBL9168322 0.67 PNMT (0.37) PNMTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5744666-A Process for preparing an alkynyl fulvene group containing compound and said compound PHILLIPS PETROLEUM COMPANY (US) 1998-04-28 US disclosed
US-5728908-A Process for preparing a bridged ligand and said bridged ligand PHILLIPS PETROLEUM COMPANY (US) 1998-03-17 US disclosed
US-5631203-A Metallocene compounds and preparation thereof containing terminal alkynes PHILLIPS PETROLEUM COMPANY (US) 1997-05-20 US disclosed