Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20214885 | 0.98 | HRH3 (0.48) | HRH3ALDH1A1MAPTPOLBKCNJ1 | |
| SCHEMBL14818235 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KCNJ1KCNH2L3MBTL1SMN1; SMN2 | |
| SCHEMBL579720 | 0.77 | POLB (0.50) | ALDH1A1MAPTPOLBKCNJ1KCNH2 | |
| SCHEMBL9973250 | 0.77 | KCNJ1 (0.53) | ALDH1A1MAPTPOLBKCNJ1KCNH2 | |
| SCHEMBL1546934 | 0.76 | HRH3 (0.50) | HRH3ALDH1A1MAPTKCNJ1SMN1; SMN2 | |
| SCHEMBL28408773 | 0.75 | MAPT (0.39) | HRH3ALDH1A1MAPTPOLBKDM4E | |
| SCHEMBL9799773 | 0.71 | ALDH1A1 (0.44) | HRH3ALDH1A1MAPTPOLBKCNH2 | |
| SCHEMBL6355550 | 0.70 | HRH3 (0.61) | HRH3ALDH1A1MAPTPOLBL3MBTL1 | |
| Nitric Acid SCHEMBL4891397 | 0.70 | HRH3 (0.42) | HRH3ALDH1A1MAPTPOLBKDM4E | |
| SCHEMBL23828671 | 0.69 | HRH3 (0.69) | HRH3ALDH1A1MAPTPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112989706-A | Tunnel lamp illumination attenuation prediction method | 东北大学 | 2021-06-18 | — | — | CN | disclosed |
| EP-3611171-A1 | METHOD FOR SYNTHESIS OF ELIGLUSTAT AND INTERMEDIATE COMPOUNDS THEREOF | Zhejiang Ausun Pharmaceutical Co., Ltd. (CN) | 2020-02-19 | — | — | EP | disclosed |
| US-8669259-B2 | Heterocyclic amide compounds as protein kinase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2014-03-11 | — | — | US | disclosed |
| US-20120208826-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS PROTEIN KINASE INHIBITORS | SCHERING CORPORATION (US) | 2012-08-16 | — | — | US | disclosed |
| US-5750802-A | (1R*, 2S)-1-phenyl-2-nitroalcohols and method for producing same | AMVAC CHEMICAL CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208826-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS PROTEIN KINASE INHIBITORS | CDK1, MTOR, GAK | HRH3 1451/4885ALDH1A1 2722/4885MAPT 710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.