Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6158841 | 0.88 | KMT2A (0.61) | ALDH1A1KMT2AHPGDPOLBCYP2C9 | |
| SCHEMBL6045130 | 0.84 | KMT2A (0.79) | ALDH1A1KMT2AHPGDPOLBSMN1; SMN2 | |
| SCHEMBL5907625 | 0.83 | KMT2A (0.63) | ALDH1A1KMT2AHPGDPOLBCYP2C9 | |
| SCHEMBL9364496 | 0.81 | KMT2A (0.61) | ALDH1A1KMT2AHPGDPOLBMEN1 | |
| SCHEMBL7438292 | 0.80 | KMT2A (0.60) | ALDH1A1KMT2AHPGDPOLBMEN1 | |
| SCHEMBL15571274 | 0.78 | LMNA (0.68) | ALDH1A1KMT2AHPGDPOLBSMN1; SMN2 | |
| SCHEMBL14519817 | 0.77 | POLB (0.54) | ALDH1A1KMT2AHPGDPOLBNPC1 | |
| SCHEMBL6160794 | 0.77 | KMT2A (0.51) | ALDH1A1KMT2AHPGDPOLBMEN1 | |
| SCHEMBL18426210 | 0.75 | KMT2A (0.58) | ALDH1A1KMT2AHPGDPOLBMEN1 | |
| SCHEMBL154367 | 0.75 | MTNR1A (0.73) | ALDH1A1HPGDPOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763465-A | 7-(2-aminoethyl) benzothiazolones | ASTRA PHARMACEUTICALS LIMITED (GB) | 1998-06-09 | — | — | US | disclosed |