Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8672148 | 0.73 | ANPEP (0.37) | — | |
| SCHEMBL9723381 | 0.72 | TSHR (0.39) | HMGCRTDP1ALDH1A1LMNAMAPT | |
| SCHEMBL1850109 | 0.69 | AOX1 (0.40) | HMGCRTDP1ALDH1A1LMNAMAPT | |
| SCHEMBL1849754 | 0.66 | TSHR (0.40) | HMGCRTDP1ALDH1A1LMNAMAPT | |
| SCHEMBL15346171 | 0.65 | — | — | |
| SCHEMBL27682034 | 0.65 | TSHR (0.39) | HMGCRTDP1ALDH1A1LMNAMAPT | |
| SCHEMBL9652021 | 0.65 | TSHR (0.48) | HMGCRTDP1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8606346 | 0.65 | MEN1 (0.52) | HMGCRTDP1ALDH1A1LMNAMAPT | |
| SCHEMBL31374414 | 0.65 | — | — | |
| SCHEMBL1849695 | 0.65 | TSHR (0.38) | HMGCRTDP1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728650-A | Herbicidal aza bisphosphonic acids and compositions containing the same | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |
| EP-0722268-A1 | HERBICIDAL AZA BISPHOSPHONIC ACID COMPOSITIONS | ZENECA LIMITED (GB) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995010188-A2 | HERBICIDAL AZA BISPHOSPHONIC ACID COMPOSITIONS | ZENECA LIMITED (GB) | 1995-04-20 | — | — | WO | disclosed |