SCHEMBL8670811

SCHEMBL8670811

CCCCCNCCNCC(C)(C)SCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 7/20 0.54
CYP1A2 P05177 2/20 0.47
CYP2D6 P10635 2/20 0.47
CYP3A4 P08684 1/20 0.47
PRMT1 Q99873 1/20 0.47
CHRM2 P08172 1/20 0.40
CYP2C19 P33261 1/20 0.38
MAOA P21397 1/20 0.38
HPGD P15428 1/20 0.38
HRH4 Q9H3N8 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6895748 0.79 CYP3A4 (0.53) SIGMAR1CYP1A2CYP2D6CYP3A4PRMT1
SCHEMBL8629391 0.77 SIGMAR1 (0.46) SIGMAR1CHRM2HRH4HRH3ALDH1A1
SCHEMBL9298906 0.74 CYP1A2 (0.47) CYP1A2CYP2D6CYP3A4PRMT1CYP2C19
SCHEMBL5922298 0.73 CHRM2 (0.74) SIGMAR1CYP1A2CYP2D6CHRM2CYP2C19
SCHEMBL9415955 0.72 CHRM2 (0.78) SIGMAR1CYP1A2CYP2D6CHRM2CYP2C19
SCHEMBL9819972 0.71 SIGMAR1 (0.85) SIGMAR1
SCHEMBL9038092 0.71 SIGMAR1 (0.85) SIGMAR1
SCHEMBL2934215 0.71 SIGMAR1 (1.00) SIGMAR1HPGDHRH3
SCHEMBL9800592 0.71 CYP1A2 (0.54) CYP1A2CYP2D6CYP3A4PRMT1CYP2C19
SCHEMBL12879664 0.70 CYP2D6 (0.68) CYP1A2CYP2D6CYP3A4PRMT1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0820313-A2 RADIOLABELED PEPTIDES FOR DIAGNOSIS AND THERAPY Diatide, Inc. (US) 1998-01-28 EP disclosed
WO-1996030055-A2 RADIOLABELED PEPTIDES FOR DIAGNOSIS AND THERAPY DIATIDE, INC. (US) 1996-10-03 WO disclosed