Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910538 | 0.83 | IDO1 (0.57) | CYP1A2CYP2D6CYP3A4PRMT1KMT2A | |
| SCHEMBL6604781 | 0.83 | KMT2A (0.56) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL6431176 | 0.77 | CYP3A4 (0.59) | CYP1A2CYP2D6CYP3A4PRMT1POLB | |
| SCHEMBL15033605 | 0.75 | KMT2A (0.48) | KMT2AMEN1POLBMAPTLMNA | |
| SCHEMBL5193497 | 0.75 | CYP3A4 (0.61) | CYP1A2CYP2D6CYP3A4PRMT1KMT2A | |
| SCHEMBL9068773 | 0.73 | CYP1A2 (0.53) | CYP1A2CYP2D6CYP3A4PRMT1POLB | |
| SCHEMBL4025556 | 0.72 | CYP2C9 (0.47) | CYP1A2CYP2D6CYP3A4POLBRIPK1 | |
| SCHEMBL12879664 | 0.72 | CYP2D6 (0.68) | CYP1A2CYP2D6CYP3A4PRMT1POLB | |
| Hydrochloric Acid SCHEMBL6895748 | 0.72 | CYP3A4 (0.53) | CYP1A2CYP2D6CYP3A4PRMT1KMT2A | |
| SCHEMBL7270339 | 0.72 | CYP1A2 (0.57) | CYP1A2CYP2D6CYP3A4PRMT1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416373-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-03-13 | — | — | EP | disclosed |