Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | PITRM1 | Q5JRX3 | 3/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.33 |
| ▸ | FAP | Q12884 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | MME | P08473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14899074 | 0.89 | CYP2C19 (0.34) | CYP2C19TSHRNFKB1FFAR3DPP4 | |
| SCHEMBL8411779 | 0.87 | ALDH1A1 (0.35) | CYP2C19TSHRNFKB1FFAR3DPP4 | |
| SCHEMBL9354755 | 0.83 | DPP4 (0.32) | CYP2C19TSHRNFKB1DPP4PITRM1 | |
| SCHEMBL7208896 | 0.83 | NPSR1 (0.33) | CYP2C19TSHRNFKB1MMEALDH1A1 | |
| SCHEMBL7208245 | 0.80 | ALDH1A1 (0.41) | TSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8277960 | 0.78 | CYP2C19 (0.41) | CYP2C19TSHRNFKB1FFAR3DPP4 | |
| SCHEMBL1874859 | 0.78 | CYP2C19 (0.36) | CYP2C19TSHRNFKB1FFAR3DPP4 | |
| SCHEMBL14979856 | 0.76 | SLC1A2 (0.46) | CYP2C19TSHRNFKB1DPP4PITRM1 | |
| SCHEMBL22746095 | 0.76 | SLC1A2 (0.46) | CYP2C19TSHRNFKB1DPP4PITRM1 | |
| SCHEMBL22746096 | 0.76 | SLC1A2 (0.46) | CYP2C19TSHRNFKB1DPP4PITRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5831119-A | Process for the preparation of aminoacetic acids with a tertiary hydrocarbon radical in the α-position, or their nitriles | HUELS AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | claimed |
| US-5831119-A | Process for the preparation of aminoacetic acids with a tertiary hydrocarbon radical in the α-position, or their nitriles | HUELS AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |