SCHEMBL8670868

SCHEMBL8670868

C=C1C(C)=C(C(=O)OC(C)(C)C)N2C(=O)[C@H](Br)[C@@H]2S1(=O)=O

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ELANE P08246 19/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8673597 1.00 ELANE (0.49) ELANE
SCHEMBL9149059 0.84 ELANE (0.69) ELANE
SCHEMBL7363263 0.84 ELANE (0.69) ELANE
SCHEMBL8668549 0.81 ELANE (0.33) ELANE
SCHEMBL8668553 0.81 ELANE (0.33) ELANE
SCHEMBL8667176 0.76 ESR1 (0.34) ELANE
SCHEMBL8667178 0.76 ESR1 (0.34) ELANE
SCHEMBL8670544 0.76 ELANE (0.72) ELANE
SCHEMBL8670547 0.76 ELANE (0.72) ELANE
SCHEMBL9755501 0.73 ELANE (0.39) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0494914-B1 2-SPIROCYCLOPROPYL CEPHALOSPORIN DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF SYNPHAR LAB INC (CA) 1998-12-23 EP disclosed
US-5264430-A Enzyme inhibitor, antiinflammatory agents, treats emphysema, cystic fibrosis and arthritis SYNPHAR LABORATORIES, INC. (CA) 1993-11-23 US disclosed
US-5264429-A Enzyme inhibitor, antiinflammatory agents, treats emphysema, cystic fibrosis and arthritis SYNPHAR LABORATORIES, INC. (CA) 1993-11-23 US disclosed