Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670547 | 1.00 | ELANE (0.72) | ELANE | |
| SCHEMBL7970632 | 0.84 | ELANE (1.00) | ELANE | |
| SCHEMBL7279397 | 0.84 | ELANE (1.00) | ELANE | |
| SCHEMBL7436386 | 0.84 | ELANE (1.00) | ELANE | |
| SCHEMBL7436377 | 0.84 | ELANE (1.00) | ELANE | |
| SCHEMBL9755497 | 0.81 | ELANE (0.50) | ELANE | |
| SCHEMBL9755499 | 0.81 | ELANE (0.50) | ELANE | |
| SCHEMBL9368293 | 0.77 | ELANE (0.62) | ELANE | |
| SCHEMBL8673597 | 0.76 | ELANE (0.49) | ELANE | |
| SCHEMBL8670868 | 0.76 | ELANE (0.49) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494914-B1 | 2-SPIROCYCLOPROPYL CEPHALOSPORIN DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | SYNPHAR LAB INC (CA) | 1998-12-23 | — | — | EP | disclosed |
| US-5264430-A | Enzyme inhibitor, antiinflammatory agents, treats emphysema, cystic fibrosis and arthritis | SYNPHAR LABORATORIES, INC. (CA) | 1993-11-23 | — | — | US | disclosed |
| US-5264429-A | Enzyme inhibitor, antiinflammatory agents, treats emphysema, cystic fibrosis and arthritis | SYNPHAR LABORATORIES, INC. (CA) | 1993-11-23 | — | — | US | disclosed |
| EP-0494914-A1 | NOVEL 2-SPIROCYCLOPROPYL CEPHALOSPORIN SULFONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | SYNPHAR LABORATORIES INC. (CA) | 1992-07-22 | — | — | EP | disclosed |
| WO-1991004977-A1 | NOVEL 2-SPIROCYCLOPROPYL CEPHALOSPORIN SULFONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | SYNPHAR LABORATORIES, INC. (CA) | 1991-04-18 | — | — | WO | disclosed |