Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7934866 | 0.99 | KMT2A (0.52) | KMT2AHTR1ASIGMAR1GSK3BHTT | |
| Hydrochloric Acid SCHEMBL7930371 | 0.84 | KMT2A (0.50) | KMT2AHTR1ASIGMAR1HTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL7929095 | 0.77 | KMT2A (0.66) | KMT2AHTR1AHTTALDH1A1KDM4E | |
| SCHEMBL15131500 | 0.77 | ALDH1A1 (0.51) | KMT2AHTTALDH1A1MAPK1MAPT | |
| Hydrochloric Acid SCHEMBL8089744 | 0.77 | SIGMAR1 (0.43) | KMT2ASIGMAR1HTTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL907064 | 0.76 | ALDH1A1 (0.64) | KMT2AHTR1AHTTALDH1A1KDM4E | |
| SCHEMBL3401703 | 0.75 | GBA1 (0.54) | SIGMAR1HTTALDH1A1KDM4EMAPK1 | |
| SCHEMBL378000 | 0.75 | GBA1 (0.54) | SIGMAR1HTTALDH1A1KDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL7932202 | 0.74 | KMT2A (0.61) | KMT2AHTR1AGSK3BHTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL7930353 | 0.74 | ALDH1A1 (0.67) | KMT2AHTR1AHTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705501-A | ADMINISTERING TO INHIBIT FORMATION OF ABNORMAL PHOSPHORYLATED PAIRED HELICAL FILAMENT EPITOPES | MOLECULAR GERIATRICS CORPORATION (US) | 1998-01-06 | — | — | US | claimed |