Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.52 |
| ▸ | BRS3 | P32247 | 2/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | CSF1R | P07333 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.50 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.50 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.48 |
| ▸ | BDKRB1 | P46663 | 8/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL562 | 0.98 | SLC6A3 (0.68) | SLC6A3SLC6A4SLC6A2LTB4R2BRS3 | |
| SCHEMBL29390423 | 0.98 | SLC6A3 (0.68) | SLC6A3SLC6A4SLC6A2LTB4R2BRS3 | |
| SCHEMBL8792048 | 0.87 | SLC6A3 (0.64) | SLC6A3SLC6A4SLC6A2LTB4R2BRS3 | |
| SCHEMBL29979869 | 0.86 | SLC6A3 (0.69) | SLC6A3SLC6A4SLC6A2LTB4R2BRS3 | |
| SCHEMBL14326964 | 0.86 | SLC6A3 (0.69) | SLC6A3SLC6A4SLC6A2LTB4R2BRS3 | |
| SCHEMBL3112718 | 0.86 | SLC6A3 (0.69) | SLC6A3SLC6A4SLC6A2LTB4R2BRS3 | |
| SCHEMBL2642187 | 0.84 | SLC6A3 (0.67) | SLC6A3SLC6A4SLC6A2LTB4R2BRS3 | |
| SCHEMBL5863187 | 0.84 | TSHR (0.57) | SLC6A3SLC6A4LTB4R2KMT2A | |
| SCHEMBL5099361 | 0.84 | SLC6A3 (0.49) | SLC6A3SLC6A4SLC6A2LTB4R2BRS3 | |
| SCHEMBL8539999 | 0.83 | SLC6A3 (0.69) | SLC6A3SLC6A4SLC6A2LTB4R2BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817674-A | ANTIOTENSIN II RECEPTOR ANTAGONISTS | ROUSSEL UCLAF (FR) | 1998-10-06 | — | — | US | disclosed |