SCHEMBL562

SCHEMBL562

COC(=O)c1ccccc1-c1ccc(CBr)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 5/20 0.68
SLC6A4 P31645 3/20 0.65
SLC6A2 P23975 1/20 0.57
LTB4R2 Q9NPC1 1/20 0.53
ROCK2 O75116 1/20 0.51
CSF1R P07333 1/20 0.51
KDR P35968 1/20 0.51
FLT3 P36888 1/20 0.51
GSK3A P49840 1/20 0.51
GSK3B P49841 1/20 0.51
CDK5 Q00535 1/20 0.51
ROCK1 Q13464 1/20 0.51
SLK Q9H2G2 1/20 0.51
IRAK4 Q9NWZ3 1/20 0.51
BRS3 P32247 2/20 0.51
BDKRB1 P46663 7/20 0.49
HTT P42858 1/20 0.48
KMT2A Q03164 1/20 0.48
AGTR1 P30556 1/20 0.47
AGTR2 P50052 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29390423 1.00 SLC6A3 (0.68) SLC6A3SLC6A4SLC6A2LTB4R2ROCK2
SCHEMBL8670912 0.98 SLC6A3 (0.66) SLC6A3SLC6A4SLC6A2LTB4R2ROCK2
SCHEMBL8792048 0.88 SLC6A3 (0.64) SLC6A3SLC6A4SLC6A2LTB4R2ROCK2
SCHEMBL29979869 0.87 SLC6A3 (0.69) SLC6A3SLC6A4SLC6A2LTB4R2ROCK2
SCHEMBL3112718 0.87 SLC6A3 (0.69) SLC6A3SLC6A4SLC6A2LTB4R2ROCK2
SCHEMBL14326964 0.87 SLC6A3 (0.69) SLC6A3SLC6A4SLC6A2LTB4R2ROCK2
SCHEMBL2642187 0.86 SLC6A3 (0.67) SLC6A3SLC6A4SLC6A2LTB4R2ROCK2
SCHEMBL5863187 0.85 TSHR (0.57) SLC6A3SLC6A4LTB4R2KMT2ALMNA
SCHEMBL5099361 0.85 SLC6A3 (0.49) SLC6A3SLC6A4SLC6A2LTB4R2ROCK2
SCHEMBL8916346 0.84 SLC6A3 (0.48) SLC6A3SLC6A4SLC6A2LTB4R2BRS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115959962-B Visible light-promoted halogenated alkane hydrodehalogenation method 中国科学院兰州化学物理研究所 2025-05-23 CN claimed
CN-114814041-B Method for detecting brominated alkanes genotoxic impurities in telmisartan by adopting liquid chromatography-mass spectrometer 浙江金立源药业有限公司 2024-05-10 CN claimed
CN-117069580-B Triclosan hapten as well as preparation method and application thereof 北京市疾病预防控制中心 2024-02-23 CN claimed
CN-117510973-A Lightweight PET decorative film and preparation process thereof 江苏新光镭射包装材料股份有限公司 2024-02-06 CN claimed
CN-117069580-A Triclosan hapten as well as preparation method and application thereof 北京市疾病预防控制中心 2023-11-17 CN claimed
CN-116813512-B Florfenicol hapten as well as preparation method and application thereof 中国农业大学 2023-11-07 CN claimed
CN-116813512-A Florfenicol hapten as well as preparation method and application thereof 中国农业大学 2023-09-29 CN claimed
CN-110156761-B Compound containing coumarin-biphenyl skeleton, preparation method and application thereof 郑州大学 2022-08-09 CN claimed
CN-114814041-A Method for detecting bromoalkane genotoxic impurities in telmisartan by adopting liquid chromatograph-mass spectrometer 浙江金立源药业有限公司 2022-07-29 CN claimed
CN-113200934-B Compound containing benzomorpholone-biphenyl skeleton and preparation method and application thereof 郑州大学 2022-05-31 CN claimed
CN-110156761-A Containing cumarin-biphenyl backbone compound, preparation method and applications 郑州大学 2019-08-23 CN claimed
US-10077242-B2 Convergent approach to the total synthesis of telmisartan via a suzuki cross-coupling reaction VIRGINIA COMMONWEALTH UNIVERSITY (US) 2018-09-18 US claimed
US-20170260146-A1 A CONVERGENT APPROACH TO THE TOTAL SYNTHESIS OF TELMISARTAN VIA A SUZUKI CROSS-COUPLING REACTION VIRGINIA COMMONWEALTH UNIVERSITY 2017-09-14 US claimed
US-7943781-B2 Process for preparing telmisartan DR. REDDY'S LABORATORIES LIMITED (IN) 2011-05-17 US claimed
EP-1805146-A4 PROCESS FOR PREPARING TELMISARTAN REDDYS LAB LTD DR (IN) 2009-01-14 EP claimed
US-20070287840-A1 Process for Preparing Telmisartan DR. REDDY'S LABORATORIES LIMITED (IN) 2007-12-13 US claimed
EP-1805146-A2 PROCESS FOR PREPARING TELMISARTAN Dr. Reddy's Laboratories Ltd. (IN) 2007-07-11 EP claimed
US-20060211866-A1 Process for the preparation of angiotensin receptor blockers and intermediates thereof GLENMARK PHARMACEUTICALS LIMITED (IN) 2006-09-21 US claimed
WO-2006044754-A2 PROCESS FOR PREPARING TELMISARTAN DR. REDDY'S LABORATORIES LTD. (IN) 2006-04-27 WO claimed
EP-0527851-B1 1H-SUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS SEARLE & CO (US) 1998-12-23 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10077242-B2 Convergent approach to the total synthesis of telmisartan via a suzuki cross-coupling reaction AGTR2, AGTR1, REN SLC6A3 1584/4885SLC6A4 1377/4885SLC6A2 1562/4885
US-20060211866-A1 Process for the preparation of angiotensin receptor blockers and intermediates thereof AGTR1, AGTR2, BDKRB1 SLC6A3 1210/4885SLC6A4 999/4885SLC6A2 1071/4885
US-20070287840-A1 Process for Preparing Telmisartan AGT, TTR, REN SLC6A3 3387/4885SLC6A4 1416/4885SLC6A2 2289/4885
US-20170260146-A1 A CONVERGENT APPROACH TO THE TOTAL SYNTHESIS OF TELMISARTAN VIA A SUZUKI CROSS-COUPLING REACTION REN, AGTR1, AGTR2 SLC6A3 1794/4885SLC6A4 1777/4885SLC6A2 1758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.