Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9231277 | 0.86 | GRIA1 (0.43) | GRIA1GRIA2GRIA3GRIA4 | |
| Hydrochloric Acid SCHEMBL9093895 | 0.84 | GRIA1 (0.42) | GRIA1GRIA2GRIA3GRIA4 | |
| Hydrochloric Acid SCHEMBL8667312 | 0.77 | HTR1B (0.41) | GRIA1GRIA2GRIA3GRIA4HTR1B | |
| Hydrochloric Acid SCHEMBL8671588 | 0.76 | HTR1D (0.61) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL9091481 | 0.74 | GRIA1 (0.58) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL5917114 | 0.72 | HTR1D (0.62) | NR2E1HTR1B | |
| SCHEMBL10487258 | 0.72 | PLAU (0.41) | NR2E1PLAU | |
| SCHEMBL7987814 | 0.70 | GRIA1 (0.50) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL9092705 | 0.70 | GRIA1 (0.40) | GRIA1GRIA2GRIA3GRIA4HTR1B | |
| SCHEMBL9092692 | 0.70 | GRIA1 (0.40) | GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721234-A | TREATING CONVULSIONS, ANXIETY, CEREBRAL HYPOXIA/ISCHEMIA, PARKINSON*S DISEASE | WARNER-LAMBERT COMPANY (US) | 1998-02-24 | — | — | US | disclosed |
| WO-1996017832-A1 | NOVEL GLUTAMATE RECEPTOR ANTAGONISTS: FUSED CYCLOALKYLQUINOXALINEDIONES | WARNER-LAMBERT COMPANY (US) | 1996-06-13 | — | — | WO | disclosed |