Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 8/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3628602 | 0.75 | NPSR1 (0.46) | KMT2AMEN1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL8385141 | 0.72 | NPSR1 (0.59) | KMT2AMEN1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL1362924 | 0.69 | MEN1 (0.37) | KMT2AMEN1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL8663762 | 0.69 | GAA (0.56) | KMT2AMEN1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL8663389 | 0.69 | GAA (0.56) | KMT2AMEN1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL12706784 | 0.68 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1CYP2C9CYP2C19 | |
| Albutoin SCHEMBL35488 | 0.68 | KMT2A (1.00) | KMT2AMEN1ALDH1A1CYP2C9CYP2C19 | |
| Albutoin SCHEMBL5053862 | 0.68 | KMT2A (1.00) | KMT2AMEN1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL12099135 | 0.67 | LMNA (0.47) | KMT2AMEN1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL22063690 | 0.67 | LMNA (0.47) | KMT2AMEN1ALDH1A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876355-A1 | 2-THIOXO-IMIDAZOLIDIN-4-ONE DERIVATIVES AND THEIR USE FOR INCREASING HDL CHOLESTEROL CONCENTRATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-11-11 | — | — | EP | claimed |
| WO-1997019932-A1 | 2-THIOXO-IMIDAZOLIDIN-4-ONE DERIVATIVES AND THEIR USE FOR INCREASING HDL CHOLESTEROL CONCENTRATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-06-05 | — | — | WO | claimed |