Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 13/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | F10 | P00742 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14214320 | 0.68 | ALDH1A1 (0.47) | MIF | |
| SCHEMBL8250520 | 0.63 | ALDH1A1 (0.46) | MIFHDAC6 | |
| SCHEMBL3986368 | 0.62 | F2 (0.44) | MIFF2F10HDAC6 | |
| SCHEMBL455228 | 0.61 | MIF (1.00) | MIFHDAC6 | |
| SCHEMBL667764 | 0.61 | MIF (1.00) | MIFHDAC6 | |
| SCHEMBL8243017 | 0.61 | MIF (0.52) | MIFHDAC6 | |
| SCHEMBL12556024 | 0.61 | MIF (0.76) | MIFHDAC6 | |
| Vgx-1027 SCHEMBL1404343 | 0.61 | MIF (0.78) | MIFHDAC6 | |
| Vgx-1027 SCHEMBL1414048 | 0.61 | MIF (0.78) | MIFHDAC6 | |
| SCHEMBL469386 | 0.61 | ALDH1A1 (0.72) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | claimed |