Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | ITGB2 | P05107 | 4/20 | 0.54 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.54 |
| ▸ | ITGAL | P20701 | 4/20 | 0.54 |
| ▸ | ACE | P12821 | 3/20 | 0.53 |
| ▸ | TACR1 | P25103 | 1/20 | 0.51 |
| ▸ | ECE1 | P42892 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetyltryptophan SCHEMBL4216450 | 0.84 | ALOX15 (0.79) | ALOX15ITGB2ICAM1ITGALACE | |
| Acetyltryptophan SCHEMBL702442 | 0.84 | ALOX15 (0.79) | ALOX15ITGB2ICAM1ITGALACE | |
| Acetyltryptophan SCHEMBL57141 | 0.84 | ALOX15 (0.79) | ALOX15ITGB2ICAM1ITGALACE | |
| Acetyltryptophan SCHEMBL29360698 | 0.84 | ALOX15 (0.79) | ALOX15ITGB2ICAM1ITGALACE | |
| Acetyltryptophan SCHEMBL57140 | 0.84 | ALOX15 (0.79) | ALOX15ITGB2ICAM1ITGALACE | |
| Acetyltryptophan SCHEMBL4216452 | 0.84 | ALOX15 (0.79) | ALOX15ITGB2ICAM1ITGALACE | |
| Acetyltryptophan SCHEMBL29401158 | 0.84 | ALOX15 (0.79) | ALOX15ITGB2ICAM1ITGALACE | |
| Acetyltryptophan SCHEMBL23933298 | 0.83 | ALOX15 (0.77) | ALOX15ITGB2ICAM1ITGALACE | |
| Acetyltryptophan SCHEMBL1427071 | 0.83 | ALOX15 (0.77) | ALOX15ITGB2ICAM1ITGALACE | |
| Acetyltryptophan SCHEMBL11471934 | 0.83 | ALOX15 (0.77) | ALOX15ITGB2ICAM1ITGALACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849781-A | Tricyclic amides | ADIR ET COMPAGNIE (FR) | 1998-12-15 | — | — | US | disclosed |
| US-5712312-A | MELATONINERGIC RECEPTOR LIGANDS, TREATMENT OF SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1998-01-27 | — | — | US | disclosed |