Acetyltryptophan

Acetyltryptophan

SCHEMBL29401158

CC(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.79
ACE P12821 3/20 0.73
ITGB2 P05107 3/20 0.70
ICAM1 P05362 3/20 0.70
ITGAL P20701 3/20 0.70
TACR1 P25103 1/20 0.69
ECE1 P42892 6/20 0.67
KDM4E B2RXH2 1/20 0.64
APAF1 O14727 1/20 0.64
POLB P06746 1/20 0.64
MAPT P10636 1/20 0.64
RECQL P46063 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
FPR2 P25090 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetyltryptophan SCHEMBL4216452 1.00 ALOX15 (0.79) ALOX15ACEITGB2ICAM1ITGAL
Acetyltryptophan SCHEMBL29360698 1.00 ALOX15 (0.79) ALOX15ACEITGB2ICAM1ITGAL
Acetyltryptophan SCHEMBL702442 1.00 ALOX15 (0.79) ALOX15ACEITGB2ICAM1ITGAL
Acetyltryptophan SCHEMBL57140 1.00 ALOX15 (0.79) ALOX15ACEITGB2ICAM1ITGAL
Acetyltryptophan SCHEMBL4216450 1.00 ALOX15 (0.79) ALOX15ACEITGB2ICAM1ITGAL
Acetyltryptophan SCHEMBL57141 1.00 ALOX15 (0.79) ALOX15ACEITGB2ICAM1ITGAL
Acetyltryptophan SCHEMBL23933298 0.99 ALOX15 (0.77) ALOX15ACEITGB2ICAM1ITGAL
Acetyltryptophan SCHEMBL1427071 0.99 ALOX15 (0.77) ALOX15ACEITGB2ICAM1ITGAL
Acetyltryptophan SCHEMBL1304487 0.99 ALOX15 (0.77) ALOX15ACEITGB2ICAM1ITGAL
Acetyltryptophan SCHEMBL11471934 0.99 ALOX15 (0.77) ALOX15ACEITGB2ICAM1ITGAL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724459-A1 PEPTIDE COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Peptidream Inc (JP) 2026-04-15 EP disclosed
US-12534439-B2 Xanthohumol derivatives and methods for making and using OREGON STATE UNIVERSITY (US) 2026-01-27 US disclosed
EP-4667480-A1 TRANSLATION INITIATION WITH EXOTIC AMINO ACIDS USING EF-P-RESPONSIVE ARTIFICIAL INITIATOR TRNA The University of Tokyo (JP) 2025-12-24 EP disclosed
US-20250298025-A1 METHODS FOR THE DETECTION AND TREATMENT OF PANCREATIC DUCTAL ADENOCARCINOMA BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2025-09-25 US disclosed
US-20250138016-A1 METHODS FOR THE DETECTION AND TREATMENT OF OVARIAN CANCER BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2025-05-01 US disclosed
WO-2025032220-A1 LIQUID BOTULINUM TOXIN FORMULATION AND USE THEREOF MERZ PHARMA GMBH & CO. KGAA (DE) 2025-02-13 WO disclosed
WO-2024252336-A1 PEPTIDE COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF PEPTIDREAM INC. (JP) 2024-12-12 WO disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
EP-4421082-A1 POLYPEPTIDE AND APPLICATION THEREOF AS CCK RECEPTOR AGONIST/ANTAGONIST Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Chinese Academy of Sciences Limited (HK) 2024-08-28 EP disclosed
WO-2024172058-A1 TRANSLATION INITIATION WITH EXOTIC AMINO ACIDS USING EF-P-RESPONSIVE ARTIFICIAL INITIATOR tRNA 国立大学法人東京大学 2024-08-22 WO disclosed
US-11970694-B2 Rapid display method in translational synthesis of peptide PEPTIDREAM INC. (JP) 2024-04-30 US disclosed
US-20240051922-A1 XANTHOHUMOL DERIVATIVES AND METHODS FOR MAKING AND USING OREGON STATE UNIVERSITY (US) 2024-02-15 US disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
US-20230324394-A1 METHODS FOR THE DETECTION AND TREATMENT OF PANCREATIC DUCTAL ADENOCARCINOMA BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2023-10-12 US disclosed
CN-116694480-A Dark She Kongjun S-LWZ20190428-3 and application thereof in preparation of rice fungus grains 中国科学院微生物研究所 2023-09-05 CN disclosed
CN-116445299-A Phellinus linteus S-LWZ20210623-1a and application thereof in preparation of rice fungus grains 中国科学院微生物研究所 2023-07-18 CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
EP-4031557-A1 METHODS FOR PRODUCING D-TRYPTOPHAN AND SUBSTITUTED D-TRYPTOPHANS The Regents of the University of California (US) 2022-07-27 EP disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534439-B2 Xanthohumol derivatives and methods for making and using MT-CO1, MT-CO2, PC ALOX15 3449/4885ACE 4473/4885ITGB2 4054/4885
US-20240051922-A1 XANTHOHUMOL DERIVATIVES AND METHODS FOR MAKING AND USING XDH, PC, TFB2M ALOX15 1777/4885ACE 3688/4885ITGB2 4853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.