SCHEMBL8671990

SCHEMBL8671990

C[CH]Cc1ccccc1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.53
ALDH1A1 P00352 6/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.49
CLCN2 P51788 1/20 0.45
HIF1A Q16665 2/20 0.44
CYP2C9 P11712 1/20 0.44
HTT P42858 2/20 0.44
TP53 P04637 1/20 0.44
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA4 P22748 2/20 0.43
CA7 P43166 2/20 0.43
CA9 Q16790 2/20 0.43
KDM4E B2RXH2 1/20 0.43
HMGB1 P09429 1/20 0.43
HPGD P15428 1/20 0.43
CA6 P23280 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7369716 0.85 FOLH1 (0.50) FOLH1ALDH1A1ALOX15TSHRCLCN2
SCHEMBL11897168 0.83 FOLH1 (0.57) FOLH1ALDH1A1ALOX15TSHRCLCN2
SCHEMBL11897138 0.83 FOLH1 (0.57) FOLH1ALDH1A1ALOX15TSHRCLCN2
SCHEMBL11897139 0.83 FOLH1 (0.57) FOLH1ALDH1A1ALOX15TSHRCLCN2
SCHEMBL1074384 0.82 FOLH1 (0.55) FOLH1ALDH1A1ALOX15TSHRCLCN2
SCHEMBL89060 0.82 FOLH1 (0.55) FOLH1ALDH1A1ALOX15TSHRHIF1A
Benzene SCHEMBL27083018 0.82 FOLH1 (0.55) FOLH1ALDH1A1ALOX15TSHRHIF1A
SCHEMBL7198618 0.81 FOLH1 (0.50) FOLH1ALDH1A1ALOX15TSHRCLCN2
SCHEMBL11094883 0.80 FOLH1 (0.53) FOLH1ALDH1A1ALOX15TSHRHIF1A
Hydrochloric Acid SCHEMBL7974299 0.80 FOLH1 (0.53) FOLH1ALDH1A1ALOX15TSHRHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0611271-B1 Sodium benzoate as a nucleating agent for monoaxially oriented polypropylene film FINA TECHNOLOGY (US) 1998-12-09 EP claimed