Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8672081 | 0.79 | MEN1 (0.41) | MAPK1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8676654 | 0.78 | KDM4E (0.47) | KDM4ECYP3A4CYP2C19L3MBTL1MAPK1 | |
| SCHEMBL8597910 | 0.76 | ANPEP (0.61) | HSD17B10ALDH1A1MEN1KMT2AANPEP | |
| SCHEMBL26433912 | 0.75 | KDM4E (0.67) | KDM4ECYP3A4CYP2C19L3MBTL1MAPK1 | |
| SCHEMBL26433902 | 0.75 | KDM4E (0.67) | KDM4ECYP3A4CYP2C19L3MBTL1MAPK1 | |
| SCHEMBL26446025 | 0.75 | KDM4E (0.67) | KDM4ECYP3A4CYP2C19L3MBTL1MAPK1 | |
| SCHEMBL12449688 | 0.74 | KDM4E (0.61) | KDM4ECYP3A4CYP2C19L3MBTL1MAPK1 | |
| SCHEMBL12384 | 0.74 | KDM4E (0.61) | KDM4ECYP3A4CYP2C19L3MBTL1MAPK1 | |
| SCHEMBL12000484 | 0.74 | KDM4E (0.61) | KDM4ECYP3A4CYP2C19L3MBTL1MAPK1 | |
| SCHEMBL8675612 | 0.74 | ANPEP (0.64) | HSD17B10ALDH1A1MEN1KMT2AANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728650-A | Herbicidal aza bisphosphonic acids and compositions containing the same | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |
| EP-0722268-A1 | HERBICIDAL AZA BISPHOSPHONIC ACID COMPOSITIONS | ZENECA LIMITED (GB) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995010188-A2 | HERBICIDAL AZA BISPHOSPHONIC ACID COMPOSITIONS | ZENECA LIMITED (GB) | 1995-04-20 | — | — | WO | disclosed |