Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP14 | P50281 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8644904 | 0.83 | ALDH1A1 (0.51) | MMP14ALDH1A1MAPTMEN1CYP2C9 | |
| SCHEMBL28563358 | 0.82 | TP53 (0.46) | ALDH1A1NPC1RAB9AMEN1CYP2C9 | |
| SCHEMBL7332917 | 0.80 | MMP14 (0.55) | MMP14ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL7366422 | 0.77 | NPC1 (0.46) | ALDH1A1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL27799342 | 0.76 | MMP14 (0.50) | MMP14ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL942189 | 0.76 | MMP14 (0.71) | MMP14ALDH1A1MAPTMEN1CYP2C9 | |
| SCHEMBL27880513 | 0.76 | MAPT (0.58) | MMP14ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL29174481 | 0.74 | KMT2A (0.59) | MMP14ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL27972856 | 0.73 | TSHR (0.41) | SMN1; SMN2GAA | |
| SCHEMBL20493467 | 0.73 | MMP14 (0.73) | MMP14ALDH1A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750735-A | CHEMICAL INTERMEDIATES FOR ANTIBIOTICS | AMERICAN CYANAMID COMPANY (US) | 1998-05-12 | — | — | US | disclosed |