Putrescine

Putrescine

SCHEMBL867233

C=C(C)C(N)=O.NCCCCN

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.67
PAOX Q6QHF9 3/20 0.50
NFKB1 P19838 2/20 0.42
CYP2D6 P10635 1/20 0.42
BLM P54132 4/20 0.40
LMNA P02545 4/20 0.40
NPSR1 Q6W5P4 2/20 0.40
THRB P10828 2/20 0.40
KMT2A Q03164 2/20 0.40
ALOX15 P16050 2/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
PLG P00747 1/20 0.40
SLC6A2 P23975 1/20 0.40
RECQL P46063 1/20 0.40
SLC6A3 Q01959 1/20 0.40
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
TSHR P16473 2/20 0.38
GABRR3 A8MPY1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10642806 0.97 TDP1 (0.63) TDP1PAOXNFKB1CYP2D6BLM
SCHEMBL18279809 0.97 TDP1 (0.63) TDP1PAOXNFKB1CYP2D6BLM
SCHEMBL29100268 0.97 TDP1 (0.63) TDP1PAOXNFKB1CYP2D6BLM
SCHEMBL18279788 0.97 TDP1 (0.63) TDP1PAOXNFKB1CYP2D6BLM
SCHEMBL8187319 0.97 TDP1 (0.63) TDP1PAOXNFKB1CYP2D6BLM
SCHEMBL8190449 0.94 TDP1 (0.67) TDP1PAOXNFKB1CYP2D6BLM
SCHEMBL6855758 0.89 DNM1 (0.56) TDP1PAOXKMT2AMEN1ALDH1A1
Hexadecylamine SCHEMBL28502153 0.89 DNM1 (0.56) TDP1PAOXKMT2AMEN1ALDH1A1
Ethylenediamine SCHEMBL10644761 0.88 TDP1 (0.75) TDP1PAOXBLMLMNATHRB
Ethylenediamine SCHEMBL8998818 0.88 TDP1 (0.75) TDP1PAOXBLMLMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9962521-B2 Shape memory materials by surface modification UNIVERSITY OF BRITISH COLUMBIA (CA) 2018-05-08 US claimed
US-20130303981-A1 SHAPE MEMORY MATERIALS BY SURFACE MODIFICATION UNIVERSITY OF BRITISH COLUMBIA (CA) 2013-11-14 US claimed
US-8575276-B2 Biomimetic compounds and synthetic methods therefor KNC NER ACQUISITION SUB, INC. (US) 2013-11-05 US claimed
WO-2012139214-A1 SHAPE MEMORY MATERIALS BY SURFACE MODIFICATION UNIVERSITY OF BRITISH COLUMBIA (CA) 2012-10-18 WO claimed
US-20120078296-A1 BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR KNC NER ACQUISITION SUB, INC. (US) 2012-03-29 US claimed
US-8030413-B2 Biomimetic compounds and synthetic methods therefor KNC NER ACQUISITION SUB, INC. (US) 2011-10-04 US claimed
US-7622533-B2 Biomimetic compounds and synthetic methods therefor NERITES CORPORATION (US) 2009-11-24 US claimed
US-9962521-B2 Shape memory materials by surface modification UNIVERSITY OF BRITISH COLUMBIA (CA) 2018-05-08 US disclosed
EP-3105286-B1 PROCESS FOR CURING (METH)ACRYLATE-CONTAINING UP OR VE RESIN AKZO NOBEL CHEMICALS INT BV (NL) 2018-04-11 EP disclosed
EP-2064251-B1 BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR KENSEY NASH CORP (US) 2017-10-25 EP disclosed
US-20170266353-A1 BIOADHESIVE COMPOUNDS AND METHODS OF SYNTHESIS AND USE DSM IP ASSETS BV (NL) 2017-09-21 US disclosed
US-20160355664-A1 PROCESS FOR CURING (METH)ACRYLATE-CONTAINING UP OR VE RESIN AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2016-12-08 US disclosed
EP-2334305-B1 BIOADHESIVE CONSTRUCTS KENSEY NASH CORP (US) 2015-04-22 EP disclosed
US-8030413-B2 Biomimetic compounds and synthetic methods therefor KNC NER ACQUISITION SUB, INC. (US) 2011-10-04 US disclosed
US-20100197868-A1 BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR NERITES CORPORATION (US) 2010-08-05 US disclosed
US-20100137903-A1 BIOADHESIVE CONSTRUCTS NERITES CORPORATION (US) 2010-06-03 US disclosed
US-7622533-B2 Biomimetic compounds and synthetic methods therefor NERITES CORPORATION (US) 2009-11-24 US disclosed
US-6046289-A FOR INHIBITING COAGULATION OF BLOOD PLATELETS, INHIBITING ADHESION OF ANIMAL CELLS, OR AS SUBSTRATE FOR CULTURING ANIMAL CELLS FUJIFILM CORPORATION (JP) 2000-04-04 US disclosed
EP-0488258-B1 Propenamide derivatives, polymers, copolymers and use thereof FUJI PHOTO FILM CO LTD (JP) 1996-04-17 EP disclosed
EP-0488258-A2 Propenamide derivatives, polymers, copolymers and use thereof FUJI PHOTO FILM CO., LTD. (JP) 1992-06-03 EP disclosed