Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 3/20 | 0.33 |
| ▸ | FNTB | P49356 | 3/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.31 |
| ▸ | RBPJ | Q06330 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | BRD2 | P25440 | 1/20 | 0.31 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670228 | 0.93 | FNTA (0.35) | FNTAFNTBPGGT1B | |
| SCHEMBL8674135 | 0.88 | HTR2B (0.32) | HTR2BPDE4D | |
| Tetrazole SCHEMBL8672479 | 0.86 | HTR2B (0.32) | HTR2BPDE4DFNTAFNTBLMNA | |
| SCHEMBL8676295 | 0.85 | FNTA (0.38) | FNTAFNTBPGGT1BNOTCH1 | |
| SCHEMBL8672617 | 0.84 | FNTA (0.41) | FNTAFNTBNOTCH1 | |
| SCHEMBL8671364 | 0.83 | FNTA (0.36) | FNTAFNTBPGGT1B | |
| SCHEMBL8669844 | 0.81 | KCNH2 (0.32) | — | |
| SCHEMBL8672394 | 0.79 | FNTA (0.39) | FNTAFNTBNOTCH1 | |
| SCHEMBL8671492 | 0.78 | FNTA (0.38) | FNTAFNTBNOTCH1BRD4BRD2 | |
| Tetrazole SCHEMBL8667938 | 0.77 | F11 (0.31) | HTR2BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843941-A | Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1998-12-01 | — | — | US | disclosed |