Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | CCKBR | P32239 | 3/20 | 0.31 |
| ▸ | CCKAR | P32238 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674135 | 0.94 | HTR2B (0.32) | — | |
| SCHEMBL8670228 | 0.87 | FNTA (0.35) | KCNH2CCKBRCCKARCTSLCTSB | |
| SCHEMBL8674225 | 0.81 | CCKBR (0.36) | KCNH2CCKBRCCKAR | |
| SCHEMBL8672880 | 0.81 | HTR2B (0.34) | — | |
| Tetrazole SCHEMBL8667938 | 0.81 | F11 (0.31) | — | |
| SCHEMBL8676295 | 0.79 | FNTA (0.38) | KCNH2CCKBRCCKAR | |
| SCHEMBL8672617 | 0.78 | FNTA (0.41) | KCNH2CCKBRCCKARCTSLCTSB | |
| SCHEMBL8671364 | 0.78 | FNTA (0.36) | KCNH2CCKBRCCKAR | |
| SCHEMBL8677108 | 0.75 | OPRK1 (0.34) | KCNH2CTSLCTSB | |
| SCHEMBL8672394 | 0.72 | FNTA (0.39) | KCNH2CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843941-A | Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1998-12-01 | — | — | US | disclosed |