Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.56 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19149798 | 0.85 | KCNN4 (0.56) | KCNN4KCNA3MMP2HTR6CYP3A4 | |
| SCHEMBL17158242 | 0.79 | KCNN4 (0.50) | KCNN4KCNA3MMP2CYP2C9LMNA | |
| SCHEMBL28565985 | 0.78 | KCNN4 (0.60) | KCNN4KCNA3MMP2HTR6LMNA | |
| SCHEMBL2570325 | 0.78 | ALDH1A1 (0.52) | KCNN4KCNA3CYP2C19LMNAGAA | |
| SCHEMBL768700 | 0.78 | KCNN4 (0.67) | KCNN4KCNA3MMP2HTR6CYP3A4 | |
| SCHEMBL28556866 | 0.77 | KCNN4 (0.59) | KCNN4KCNA3MMP2HTR6LMNA | |
| SCHEMBL28565008 | 0.77 | KCNN4 (0.59) | KCNN4KCNA3MMP2HTR6LMNA | |
| SCHEMBL1495922 | 0.75 | KCNN4 (0.64) | KCNN4KCNA3MMP2HTR6CYP3A4 | |
| SCHEMBL8672389 | 0.75 | KCNN4 (0.60) | KCNN4KCNA3MMP2HTR6CYP3A4 | |
| SCHEMBL28665779 | 0.74 | KCNA3 (0.89) | KCNN4KCNA3MMP2HTR6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710150-A | ARGININE VASOPRESSIN ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0716083-A1 | BENZAZEPINE DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND INTERMEDIATE FOR THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-06-12 | — | — | EP | disclosed |