SCHEMBL8673125

SCHEMBL8673125

CN(C)C(=O)C1CCCS1(=O)=O

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GLI1 P08151 1/20 0.36
CTSB P07858 1/20 0.31
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10652010 0.76 ITGB1 (0.31)
SCHEMBL20450494 0.73 ITGB1 (0.34)
SCHEMBL3533041 0.73 ITGB1 (0.34)
SCHEMBL20450497 0.73 ITGB1 (0.34)
SCHEMBL29740025 0.71 EPHX1 (0.32) GLI1
SCHEMBL8773168 0.71 ITGB1 (0.36)
SCHEMBL10652185 0.71
SCHEMBL19550447 0.67 KDM4E (0.34)
SCHEMBL14109637 0.67 KDM4E (0.34)
SCHEMBL7443339 0.67 L3MBTL1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4476334-A ETHANOL FROM METHANOL, CARBON MONOXIDE HYDROGEN WITH MINIMUM PRODUCTION OF WATER; MANGANESE CARBONYL CATALYST THE UNITED STATES DEPARTMENT OF ENERGY (US) 1984-10-09 US claimed
US-5852015-A Triazine containing anionic compounds useful as antiviral agents AMERICAN CYANAMID COMPANY (US) 1998-12-22 US disclosed
US-4087461-A 6(H)-5,10-SECO-4,5-DIENEKETO STEROIDS THE JOHNS HOPKINS UNIVERSITY (US) 1978-05-02 US disclosed
US-4059630-A Anti-androgenic steroids THE JOHNS HOPKINS UNIVERSITY (US) 1977-11-22 US disclosed