SCHEMBL8773168

SCHEMBL8773168

COC(=O)C1CCCS1(=O)=O

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ITGB1 P05556 1/20 0.36
ITGA4 P13612 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM3 P20309 1/20 0.33
PPM1B O75688 1/20 0.32
PTPN1 P18031 1/20 0.32
PPP1CC P36873 1/20 0.32
TP53 P04637 1/20 0.32
ALDH1A1 P00352 2/20 0.31
POLB P06746 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA7 P36544 1/20 0.31
CHRNA4 P43681 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6608989 0.94 SMN1; SMN2 (0.36) ITGB1ITGA4SMN1; SMN2CHRM2CHRM4
SCHEMBL7443339 0.79 L3MBTL1 (0.40) PPM1BPTPN1PPP1CCALDH1A1
SCHEMBL70158 0.78 CHRM2 (0.39) SMN1; SMN2CHRM2CHRM4CHRM3PPM1B
SCHEMBL10652010 0.76 ITGB1 (0.31) ITGB1ITGA4
SCHEMBL3533041 0.73 ITGB1 (0.34) ITGB1ITGA4POLB
SCHEMBL20450494 0.73 ITGB1 (0.34) ITGB1ITGA4POLB
SCHEMBL20450497 0.73 ITGB1 (0.34) ITGB1ITGA4POLB
SCHEMBL29740025 0.71 EPHX1 (0.32) ITGB1ITGA4
SCHEMBL8673125 0.71 GLI1 (0.36)
SCHEMBL10652185 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0671380-B1 Process for the catalytic splitting off of carboxylic ester and acyl groups from organic compounds BASF AG (DE) 1997-10-29 EP disclosed
US-5532386-A CATALYTIC CARBONIC ESTER AND A TERTIARY AMINE BASF AKTIENGESELLSCHAFT (DE) 1996-07-02 US disclosed
EP-0671380-A1 Process for the catalytic splitting off of carboxylic ester and acyl groups from organic compounds BASF AKTIENGESELLSCHAFT (DE) 1995-09-13 EP disclosed